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    Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer

    Increased glucose consumption is a hallmark of cancer cells. The increased consumption and subsequent metabolism of glucose during proliferation creates the need for a constant supply of NAD, a co-factor in gl...

    E A Hanse, C Ruan, M Kachman, D Wang, X H Lowman, A Kelekar in Oncogene (2017)