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Chapter
Malunions of the Tibial Shaft
Tibial shaft malunions occur when the tibia has healed in an inappropriate position that affects the mechanical function and axis of the lower limb. Patients with tibial malunions often experience significant ...
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Article
AroER tri-screen™ is a novel functional assay to estimate both estrogenic and estrogen precursor activity of chemicals or biological specimens
The purpose of the study is to define AroER tri-screen’s utility for identifying endocrine-disrupting chemicals (EDCs) that target aromatase and/or estrogen receptor (ER), and to measure the total estrogenic ...
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Article
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade
Apo2L/TRAIL is actively investigated as a novel targeted agent to directly induce apoptosis of susceptible cancer cells. Apo2L/TRAIL-refractory cells can be sensitized to the cytotoxic effect of this ligand by...
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Chapter
A Second Generation Solid-phase Protein Sequencer: The Prosequencer™
The solid-phase version of the Edman degradation, first described over 20 years ago (Laursen, 1966) and later automated (Laursen, 1971), takes advantage of the principle that proteins which are covalently link...