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Article
Effects of mutating different steroidogenic factor-1 protein regions on gene regulation
The involvement of cyclic adenosine monophosphate cAMP-dependent protein kinase A (PKA) in the regulation of the steroidogenic acute regulatory protein (StAR) and the high-density lipoprotein receptor (HDL-R) ...
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Article
Characterization of a steroidogenic factor-1-binding site found in promoter of sterol carrier protein-2 gene
Sterol carrier protein-2 (SCP2) is thought to mediate intracellular cholesterol transport in steroidogenic tissues. To elucidate the mechanism underlying the expression of this gene, a 300-bp fragment of the S...
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Article
Repression of the rat steroidogenic acute regulatory (StAR) protein gene by PGF2α is modulated by the negative transcription factor DAX-1
The steroidogenic acute regulatory protein (StAR) is thought to mediate the rapid increase in steroid hormone biosynthesis by facilitating cholesterol transport to the inner mitochondrial membrane. Recent stud...
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Article
Expression and hormonal regulation of the high-density lipoprotein (HDL) receptor scavenger receptor class B type I messenger ribonucleic acid in the rat ovary
Since cholesterol delivery to the ovary is an essential regulated step in steroidogenesis, mRNA levels for the Scavenger Receptor Class B Type I (SR-BI), a putative high-density lipoprotein receptor (HDL-R), w...
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Article
Hormone and prostaglandin F2α regulation of messenger ribonucleic acid encoding steroidogenic acute regulatory protein in human corpora lutea
Steroidogenic acute regulatory (StAR) protein mediates the rapid increase in steroid hormone biosynthesis in response to tropic hormones by facilitating transport of cholesterol into the inner mitochondrial me...