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  1. No Access

    Article

    A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

    Initiation of T-lymphocyte proliferation by mitogen or antigen involves a cascade of gene activation events. Thus, by the time mitogen-activated T cells have reached the G1/S interface, many genes that are transc...

    Reino Heikkila, Gisela Schwab, Eric Wickstrom, Shee Loong Loke, Dov H. Pluznik… in Nature (1987)

  2. No Access

    Book and Conference Proceedings

    Experimental Hematology Today—1985

    Selected Papers from the 14th Annual Meeting of the International Society for Experimental Hematology, July 14–18, 1985, Jerusalem, Israel

    S. J. Baum, Dov H. Pluznik… in Experimental Hematology Today (1986)

  3. No Access

    Chapter and Conference Paper

    Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy between Phorbol Esters and Calcium Ionophores

    In many secretory systems receptor triggering by agonists is followed by inositol phospholipid breakdown to diacylglycerol (DAG) and inositol triphosphate (InsP3). DAG activates protein kinase C (PK-C) and Ins...

    Dov H. Pluznik, Stephan E. Mergenhagen in Experimental Hematology Today—1985 (1986)

  4. No Access

    Chapter

    Production of Colony-Stimulating Factor (CSF) by Bone Marrow Cells Stimulated with Lipopolysaccharide (LPS) and Phorbol Esters

    Colony stimulating factors (CSF) are glycoproteins which regulate the proliferation and differentiation of committed hemopoietic stem cells into mature granulocytes and macrophages. Murine spleen cells are one...

    Dov H. Pluznik, Stephan E. Mergenhagen in Immunobiology and Immunopharmacology of Ba… (1986)

  5. No Access

    Chapter

    Endotoxin-Induced Release of Colony-Stimulating Factor

    The introduction of an in vitro technique for cloning granulocyte and macrophage precursor cells by Pluznik and Sachs (1965) and Bradley and Metcalf (1966) provided a new approach to the evaluation of the regulat...

    Dov H. Pluznik in Beneficial Effects of Endotoxins (1983)

  6. No Access

    Chapter and Conference Paper

    Cellular Requirements for Induction of Colony-Stimulating Factor in Lymphoid Cell Cultures Stimulated by T- and B-Cell Mitogens

    The clonal growth of hemopoietic cells in vitro into colonies of granulocytes and/or macrophages requires the presence of a stimulatory substance designated colony-stimulating factor (CSF) (7,21). Data from vario...

    Ron N. Apte, Eliahu Heller, Chanita F. Hertogs… in Experimental Hematology Today 1978 (1978)

  7. No Access

    Article

    Inhibition and reversal of wheat germ agglutinin-induced caps by concanavalin A

    ASSEMBLY of cell-surface components at one pole of the cell membrane, as a result of cross linkage with specific ligands, can be visualised by using labelled ligands. Such a demonstration of topographic change...

    SHLOMO LUSTIG, Dov H. PLUZNIK in Nature (1976)

  8. No Access

    Chapter

    Differential Responses of Macrophage Precursors and Antibody Forming Cells to Immunization

    Participation of macrophages in immune responses has been shown in many experiments using various methods (1) (2) (3) (4) (5). It has also been demonstrated that antibody forming cells and their precursors pro...

    Dov H. Pluznik, V. Rotter in The Reticuloendothelial System and Immune Phenomena (1971)