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  1. Article

    Open Access

    The lincRNA JUNI regulates the stress-dependent induction of c-Jun, cellular migration and survival through the modulation of the DUSP14-JNK axis

    Cancer cells employ adaptive mechanisms to survive various stressors, including genotoxic drugs. Understanding the factors promoting survival is crucial for develo** effective treatments. In this study, we u...

    Vikash Kumar, Xavier Sabaté-Cadenas, Isha Soni, Esther Stern, Carine Vias… in Oncogene (2024)

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  2. No Access

    Article

    ATM is a target for positive regulation by E2F-1

    The E2F-1 transcription factor is a critical downstream target of the tumor suppressor, RB. When activated, E2F-1 induces cell proliferation. In addition, deregulation of E2F-1 constitutes an oncogenic stress ...

    Eli Berkovich, Doron Ginsberg in Oncogene (2003)

  3. No Access

    Article

    E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

    The E2F family of transcription factors plays a pivotal role in the regulation of cell proliferation in higher eukaryotes. We used DNA microarrays and cell lines containing either inducible E2F-1 or inducible ...

    Shirley Polager, Yael Kalma, Eli Berkovich, Doron Ginsberg in Oncogene (2002)

  4. No Access

    Article

    Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2

    The transcription factor E2F-1 plays a pivotal role in the regulation of G1/S transition in higher eukaryotes cell cycle. We used a cell line containing an inducible E2F-1 and oligonucleotide microarray analys...

    Yael Kalma, Lea Marash, Yocheved Lamed, Doron Ginsberg in Oncogene (2001)