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    Biosynthesis of Methoxymalonyl-acyl Carrier Protein (ACP) as an Extender Unit for Bafilomycin Polyketide in Streptomyces griseus DSM 2608

    Bafilomycins belong to the 16-membered macrolactone family plecomacrolide antibiotics. In the bafilomycin biosynthetic gene cluster of Streptomyces griseus DSM 2608, five polyketide synthase (PKS) genes coding 12...

    Nguyen Phan Kieu Hanh, Jae Yoon Hwang in Biotechnology and Bioprocess Engineering (2018)

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    Current status and perspectives of biopharmaceutical drugs

    Since the first approval of recombinant human insulin three decades ago, more than 150 biopharmaceutical drugs have been marketed, and some of them became blockbuster drugs in market size. The patent expiratio...

    Jae Kuk Ryu, Hyo Sun Kim, Doo Hyun Nam in Biotechnology and Bioprocess Engineering (2012)

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    Immobilization of Streptomyces phospholipase D on a Dowex macroporous resin

    The immobilization of phospholipase D produced by Streptomyces sp. YU100 was evaluated to see it would be practical for industrial applications. To accomplish this, the purified enzyme, which contained 53 unit/mg...

    Jei Oh Yon, Ji Seon Lee, Bo Geum Kim in Biotechnology and Bioprocess Engineering (2008)

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    Production and physicochemical characterization of β-glucan produced byPaenibacillus polymyxa JB115

    This study was conducted to develop a bacterial glucan as an animal feed additive. A novel glucan-producing bacterium.Paenibacillus polymyxa JB115, was isolated from Korean soil. The glucan, JB115-BG, produced by

    Hee-Kyoung Jung, Joo-Heon Hong, Seung-Chun Park in Biotechnology and Bioprocess Engineering (2007)

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    Lactic acid fermentation of Chinese yam (Dioscorea batatas Decne) flour and its pharmacological effect on gastrointestinal function in rat model

    To develop a health-aid preparation of Chinese yam (Dioscorea batatas Decne), lactic acid fermentation was attempted using a mixed starter comprising ofLactobacillus acidophilus, Streptococcus thermophilus, andBi...

    Kyung Ok Shin, Jeong Ryae Jeon, Ji Seon Lee in Biotechnology and Bioprocess Engineering (2006)

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    Cloning and sequencing of a novel glutaryl acylase β-subunit gene ofPseudomonas cepacia BY21 from bioinformatics

    Pseudomonas cepacia BY21 was found to produce glutaryl acylase that is capable of deacylating glutaryl-7-aminocephalosporanic acid (glutaryl-7-ACA) to 7-aminocephalosporanic acid (7-ACA),...

    Yoo-Seok Jeong, Hyo-** Yoo, Sang-Dal Kim in Biotechnology and Bioprocess Engineering (2005)

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    Production and purification of single chain human insulin precursors with various fusion peptides

    For the production and purification of a single chain human insulin precursor four types of fusion peptides β-galactosidase (LacZ), maltose binding protein (MBP), glutathione-S-transferase (GST), and (His)6-tagge...

    Chung Woo Cho, Sun Ho Park, Doo Hyun Nam in Biotechnology and Bioprocess Engineering (2001)

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    Utilization of DNA marker-assisted selection in Korean native animals

    The recent progress of DNA technologies including DNA fingerprinting (DFP) and random amplified DNA polymorphism (RAPD) analysis make it possible to identify the specific genetic traits of animals and to analy...

    Jung-Sou Yeo, Jae-Woo Kim, Tae-Kyung Chang in Biotechnology and Bioprocess Engineering (2000)

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    Identification of genetic markers for Korean native cattle (Hanwoo) by RAPD analysis

    In order to develop the specific genetic marker for Korean native cattle (Hanwoo), randomly amplified polymorphic DNA (RAPD) analysis of 6 different cattle breeds was attempted by using 38 decamer primers. In ...

    Jung Sou Yeo, Ji Sun Lee, Chang Hee Lee in Biotechnology and Bioprocess Engineering (2000)

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    Biomolecular engineering and drug development

    Biomolecular engineering is a technology to create novel structures of high-value biomolecules for use in medicine and industry, through the directed alteration of proteins and/or biologically active molecules...

    Doo-Hyun Nam, Dewey D. Y. Ryu in Biotechnology and Bioprocess Engineering (1999)

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    Anaerobic respiration of superoxide dismutase-deficientSaccharomyces cerevisiae under oxidative stress

    The ethanol productivity of superoxide dismutase (SOD)-deficient mutants ofSaccharomyces cerevisiae was examined under the oxidative stress by Paraquat. It was observed that MnSOD-deficient mutant ofS. cerevisiae

    Sun Mi Lee, Doo Hyun Nam in Biotechnology and Bioprocess Engineering (1998)