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Article
Open AccessChanges of PK/PD of Meropenem in patients with abdominal septic shock and exploration of clinical rational administration plan: a prospective exploratory study
This study aimed to explore the changes of pharmacokinetic parameters after meropenem in patients with abdominal septic shock after gastrointestinal perforation, and to simulate the probability of different do...
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Article
Open AccessEfficacy and safety of PD-1 inhibitors in recurrent or metastatic nasopharyngeal carcinoma patients after failure of platinum-containing regimens: a systematic review and meta-analysis
There is a lack of standard salvage treatment options for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) that has failed platinum-containing regimens. Breakthroughs in immunotherapy have opened up n...
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Article
Erk5 functions in modulation of zebrafish intestinal permeability
The intestine of zebrafish consists of mucosa, muscularis and serosa. Intestinal epithelial cells (IECs) act as a physical and biochemical barrier to protect against invasion by external commensal bacteria. Ce...
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Article
Open AccessAnalysis of the N-glycosylation profiles of the spike proteins from the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2
N-Glycosylation plays an important role in the structure and function of membrane and secreted proteins. Viral proteins used in cell entry are often extensively glycosylated to assist in protein folding, provi...
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Article
Open AccessPerformance analysis of the BDSBAS-B1C message in trial operation stage
BeiDou Satellite-based Augmentation System (BDSBAS) has come into the trial operation stage since July, 2020. To evaluate the characteristic of the augmentation message in BDSBAS-B1C signal, the effectiveness ...
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Article
Open AccessInvestigation of Hippo pathway-related prognostic lncRNAs and molecular subtypes in liver hepatocellular carcinoma
This study aimed to investigate Hippo pathway-related prognostic long noncoding RNAs (lncRNAs) and their prognostic value in liver hepatocellular carcinoma (LIHC). Expression and clinical data regarding LIHC w...
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Chapter and Conference Paper
A Study on Vulnerability Code Labeling Method in Open-Source C Programs
Various existing vulnerability databases and open-source code platforms have accumulated a large amount of vulnerability information, and extracting vulnerability code samples from this information can help re...
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Chapter and Conference Paper
Automatic Grading of Student Code with Similarity Measurement
Nowadays, online judges are extensively used for automatically grading student code. However, they grade code by only counting the number of passed test cases, which is not fair for assessing the overall quali...
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Article
Open AccessSex-Specific Association Between Iron Status and the Predicted 10-Year Risk for Atherosclerotic Cardiovascular Disease in Hypertensive Patients
Serum ferritin (SF) and haemoglobin (Hb) are widely used in clinical practice to assess iron status. Studies exploring the relationship of SF and Hb with atherosclerotic cardiovascular disease (ASCVD) risk hav...
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Article
General toxicity and genotoxicity of alternariol: a novel 28-day multi-endpoint assessment in male Sprague–Dawley rats
Alternariol (AOH) is one of the toxins of Alternaria, and it has been widely detected in a variety of foods. It has been reported to be cytotoxic, dermally toxic, genotoxic, and potentially carcinogenic in vitro....
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Article
Performance analysis of two RDSS positioning modes of BeiDou-3 system
The BeiDou-3 global satellite navigation system (BDS-3) provides two radio determination satellite service (RDSS) positioning services for users, i.e., the traditional RDSS (TRDSS) positioning of the BeiDou-2 ...
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Article
Genoty**-by-sequencing and genome-wide association study reveal genetic diversity and loci controlling agronomic traits in triticale
The genetic diversity and loci underlying agronomic traits were analyzed by the reads coverage and genome-wide association study based genoty**-by-sequencing in a diverse population consistin...
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Article
Open AccessN-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry
N-glycosylation plays an important role in the structure and function of membrane and secreted proteins. The spike protein on the surface of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), th...
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Article
Hybrid MPI/OpenMP parallel asynchronous distributed alternating direction method of multipliers
The distributed alternating direction method of multipliers (ADMM) is one of the most widely used algorithms to solve large-scale optimization problems. Since the memory consumption, communication cost and con...
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Article
Full-ISL clock offset estimation and prediction algorithm for BDS3
The Ka-band dual one-way measurements from Inter-Satellite Link (ISL) devices equipped on the third-generation Beidou Navigation Satellite System (BDS3) follow a time division multiple access (TDMA) structure ...
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Article
HSAC-ALADMM: an asynchronous lazy ADMM algorithm based on hierarchical sparse allreduce communication
The distributed alternating direction method of multipliers (ADMM) is an effective algorithm for solving large-scale optimization problems. However, its high communication cost limits its scalability. An async...
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Chapter and Conference Paper
Test and Evaluation of the Distributed Autonomous Orbit Determination with the BDS Inter-satellite Ranging Data
The new generation satellites of the BeiDou navigation satellite system (BDS) all carry the inter-satellite payload in Ka band, which can support the realization of the inter-satellite ranging and information ...
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Chapter and Conference Paper
Comparison of RDSS Timing for BD-2 and BD-3 System
With the launching of BD-3 satellites, Beidou navigation satellite system is going to the global service operation. Therefore, this paper study the RDSS timing principle of BD-2 and BD-3 systematically. By ana...
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Article
Open AccessSensitive detection of type G botulinum neurotoxin through Endopep-MS peptide substrate optimization
Clostridium botulinum produces botulinum neurotoxins (BoNTs) that are one of the most poisonous substances. In order to respond to public health emergencies, there is a need to develop sensitive and specific meth...
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Article
Open AccessN-doped Carbon Coated CoO Nanowire Arrays Derived from Zeolitic Imidazolate Framework-67 as Binder-free Anodes for High-performance Lithium Storage
To realize large lithium storage capacity and excellent rate capability lithium ion batteries, highly electrochemically active materials and rational design of structure are desirable. Here, we successfully sy...
