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  1. Article

    Open Access

    Development of orthogonal aminoacyl-tRNA synthetase mutant for incorporating a non-canonical amino acid

    Genetic code expansion involves introducing non-canonical amino acids (ncAAs) with unique functional groups into proteins to broaden their applications. Orthogonal aminoacyl tRNA synthetase (aaRS), essential f...

    Dongheon Lee, Ja Gyung Kim, Tae Wan Kim, Jong-il Choi in AMB Express (2024)

  2. Article

    Open Access

    Author Correction: Optimal view detection for ultrasound-guided supraclavicular block using deep learning approaches

    Yumin Jo, Dongheon Lee, Donghyeon Baek, Bo Kyung Choi, Nisan Aryal in Scientific Reports (2023)

  3. Article

    Open Access

    Optimal view detection for ultrasound-guided supraclavicular block using deep learning approaches

    Successful ultrasound-guided supraclavicular block (SCB) requires the understanding of sonoanatomy and identification of the optimal view. Segmentation using a convolutional neural network (CNN) is limited in ...

    Yumin Jo, Dongheon Lee, Donghyeon Baek, Bo Kyung Choi, Nisan Aryal in Scientific Reports (2023)

  4. No Access

    Article

    Development of Orthogonal Aminoacyl tRNA Synthetase Mutant with Enhanced Incorporation Ability with Para-azido-L-phenylalanine

    Orthogonal aminoacyl tRNA synthetase (aaRS)/tRNA pairs are an efficient tool for the site-specific introduction of para-azido-L-phenylalanine (pAzF), a non-canonical amino acid, into the amber codon of protein...

    Dongheon Lee, Min-Kyu Kim, Jong-il Choi in Biotechnology and Bioprocess Engineering (2023)

  5. No Access

    Article

    Programmable synthetic biomolecular condensates for cellular control

    The formation of biomolecular condensates mediated by a coupling of associative and segregative phase transitions plays a critical role in controlling diverse cellular functions in nature. This has inspired th...

    Yifan Dai, Mina Farag, Dongheon Lee, **angze Zeng, Kyeri Kim in Nature Chemical Biology (2023)

  6. Article

    Open Access

    Using 2D qNMR analysis to distinguish between frozen and frozen/thawed chicken meat and evaluate freshness

    We identified key metabolites reflecting microbial spoilage and differentiated unfrozen meat from frozen/thawed (FT) using 2D qNMR analysis. Unfrozen and FT chicken breasts were prepared, individually aerobica...

    Hyun Cheol Kim, Ki Ho Baek, Yee Eun Lee, Taemin Kang, Hyun Jun Kim in npj Science of Food (2022)

  7. No Access

    Article

    Augmented Reality-Based Visual Cue for Guiding Central Catheter Insertion in Pediatric Oncologic Patients

    Pediatric hemato-oncologic patients require central catheters for chemotherapy, and the junction of the superior vena cava and right atrium is considered the ideal location for catheter tips. Skin landmarks or...

    Joong Kee Youn, Dongheon Lee, Dayoung Ko, Inhwa Yeom in World Journal of Surgery (2022)

  8. Article

    Open Access

    Effect of an anti-adhesion agent on vision-based assessment of cervical adhesions after thyroid surgery: randomized, placebo-controlled trial

    Many patients experience cervical adhesions after thyroid surgery. To date, however, no studies have objectively measured the effects of anti-adhesion agents on cervical adhesion symptoms. This study evaluated...

    Hyeong Won Yu, Dongheon Lee, Keunchul Lee, Su-** Kim, Young Jun Chai in Scientific Reports (2021)

  9. Article

    Open Access

    A band-gap database for semiconducting inorganic materials calculated with hybrid functional

    Semiconducting inorganic materials with band gaps ranging between 0 and 5 eV constitute major components in electronic, optoelectronic and photovoltaic devices. Since the band gap is a primary material propert...

    Sangtae Kim, Miso Lee, Changho Hong, Youngchae Yoon, Hyungmin An in Scientific Data (2020)

  10. No Access

    Article

    CT-based deep learning model to differentiate invasive pulmonary adenocarcinomas appearing as subsolid nodules among surgical candidates: comparison of the diagnostic performance with a size-based logistic model and radiologists

    To evaluate the deep learning models for differentiating invasive pulmonary adenocarcinomas (IACs) among subsolid nodules (SSNs) considered for resection in a retrospective diagnostic cohort in comparison with...

    Hyung** Kim, Dongheon Lee, Woo Sang Cho, Jung Chan Lee, ** Mo Goo in European Radiology (2020)

  11. Article

    Open Access

    Vision-based tracking system for augmented reality to localize recurrent laryngeal nerve during robotic thyroid surgery

    We adopted a vision-based tracking system for augmented reality (AR), and evaluated whether it helped surgeons to localize the recurrent laryngeal nerve (RLN) during robotic thyroid surgery. We constructed an ...

    Dongheon Lee, Hyeong Won Yu, Seunglee Kim, ** Yoon, Keunchul Lee in Scientific Reports (2020)

  12. Article

    Open Access

    Hetero-Multivalency of Pseudomonas aeruginosa Lectin LecA Binding to Model Membranes

    A single glycan-lectin interaction is often weak and semi-specific. Multiple binding domains in a single lectin can bind with multiple glycan molecules simultaneously, making it difficult for the classic “lock...

    Nolan C. Worstell, Akshi Singla, Panatda Saenkham, Thushara Galbadage in Scientific Reports (2018)

  13. Article

    The effect of prenatal TVOC exposure on birth and infantile weight: the Mothers and Children’s Environmental Health study

    Volatile organic compounds (VOCs) might restrict prenatal and postnatal growth. However, the effect of the exposure of prenatal VOCs on postnatal growth has not been studied sufficiently. Thus, we investigated...

    Moonhee Chang, Hyesook Park, Mina Ha, Yun-Chul Hong, Youn-Hee Lim in Pediatric Research (2017)

  14. Article

    Open Access

    Property database for single-element do** in ZnO obtained by automated first-principles calculations

    Throughout the past decades, doped-ZnO has been widely used in various optical, electrical, magnetic, and energy devices. While almost every element in the Periodic Table was doped in ZnO, the systematic compu...

    Kanghoon Yim, Joohee Lee, Dongheon Lee, Miso Lee, Eunae Cho in Scientific Reports (2017)

  15. No Access

    Article

    Hepatitis B Virus Vector Carries a Foreign Gene into Liver Cells In Vitro

    Hepatitis B viruses (HBV) specifically target the liver, where they efficiently infect quiescent hepatocytes. Thus, HBV virus has potential to be used as vectors for liver-directed gene transfer. We constructe...

    Junhee Yoo, **kyung Rho, Dongheon Lee, Suho Shin, Guhung Jung in Virus Genes (2002)