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Article
Open AccessStress-constrained topology optimization using approximate reanalysis with on-the-fly reduced order modeling
Most of the methods used today for handling local stress constraints in topology optimization, fail to directly address the non-self-adjointness of the stress-constrained topology optimization problem. This in...
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Article
Accelerating Large-scale Topology Optimization: State-of-the-Art and Challenges
Large-scale structural topology optimization has always suffered from prohibitively high computational costs that have till date hindered its widespread use in industrial design. The first and major contributo...
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Chapter and Conference Paper
Topology Optimization of Structures Using Higher Order Finite Elements in Analysis
optimization in general progresses with numerical instability i.e. checkerboard patterns if no filtering radius is used i.e. imposement of minimum length scale. Many studies are done in past decades...
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Article
On-the-fly model reduction for large-scale structural topology optimization using principal components analysis
Despite a solid theoretical foundation and straightforward application to structural design problems, 3D topology optimization still suffers from a prohibitively high computational effort that hinders its wide...
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Article
Multi-grid reduced-order topology optimization
Additive printing allows the “single step” production of virtually any complex mechanical component. However, the manufacturing process involves a layer-by-layer deposition of material, which leads to an aniso...
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Article
Effect of intramuscular electro-acupuncture-mediatedVEGF gene transfer on experimental limb ischemia
To investigate the feasibility of intramuscular electro-acupuncture-mediatedVEGF gene transfer on experimental limb ischemia, the transcription and expression ofVEGF gene have been detected with RT-PCR and immuno...
