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Article
Reduction of allergy effects of peanut sprout extract in a systemic anaphylaxis food allergy mouse model
Peanut allergy is a major cause of food-induced anaphylaxis and subsequent fatality. Food allergies are becoming an increasingly important global health issue. This study was undertaken to verify the effects o...
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Article
A Study on Simulation Based Validation of Optimized Design of High Precision Rotating Unit for Processing Machinery
With the rapid development of processing technology, the demand for precision, durability and NVH performance of processing machinery has also increased. This paper presents an optimally designed gear train co...
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Article
Open AccessZooplankton and micronekton respond to climate fluctuations in the Amundsen Sea polynya, Antarctica
The vertical migration of zooplankton and micronekton (hereafter ‘zooplankton’) has ramifications throughout the food web. Here, we present the first evidence that climate fluctuations affect the vertical migr...
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Article
Open AccessAqueous and ethanolic extracts of welsh onion, Allium fistulosum, attenuate high-fat diet-induced obesity
Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A. fistulosum ethanoli...
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Article
The promotion of hair regrowth by topical application of a Perilla frutescens extract through increased cell viability and antagonism of testosterone and dihydrotestosterone
This study investigated the potential hair regrowth effects associated with a plant extract of Perilla frutescens, which was selected due to its putative hair regrowth activity. Extracts were prepared from dried
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Article
Identification of the S locus core sequences determining self-incompatibility and S multigene family from draft genome sequences of radish (Raphanus sativus L.)
The S core and its flanking sequences were identified from two independent draft genome sequences of radish (Raphanus sativus L.). After gap-filling with PCR, the S core regions and full-length S receptor kinase ...
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Article
Open AccessAntiplatelet mechanism of an herbal mixture prepared from the extracts of Phyllostachys pubescens leaves and Prunus mume fruits
Bamboo (Phyllostachys pubescens) leaves and Japanese apricot (Mume fructus) fruit are traditionally recognized to be safe herbs broadly used for food and medicinal purposes in Southeast Asia. Our group previously...
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Article
Open AccessEffects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice
Gout is an inflammatory condition induced by the deposition of monosodium urate (MSU) crystals in joints and soft tissues, and it can lead to acute or chronic arthritis. MSU are pro-inflammatory stimuli that c...
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Article
Open AccessAnti-obesity activity, acute toxicity, and chemical constituents of aqueous and ethanol Viola mandshurica extracts
Viola mandshurica has traditionally been used as an expectorant, diuretic, and anti-inflammatory drug. The present study was designed to test the hypothesis that low doses of two diffe...
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Article
Open AccessThe acquisition of novel N-glycosylation sites in conserved proteins during human evolution
N-linked protein glycosylation plays an important role in various biological processes, including protein folding and trafficking, and cell adhesion and signaling. The acquisition of a novel N-glycosylation si...
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Article
Retroduplication and loss of parental genes is a mechanism for the generation of intronless genes in Ciona intestinalis and Ciona savignyi
Tunicates, the sister clade of vertebrates, have miniature genomes and numerous intronless genes compared to other animals. It is still unclear how the tunicates acquired such a large number of intronless gene...
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Article
Stereotypical Beliefs on Old Korean Workers
In South Korea, it is a widespread occurrence that old workers are the first victims of employment restructuring and age limit regulations during recruitment. As age discrimination in the workplace is related ...
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Article
Open AccessDohaekseunggi-tang extract inhibits obesity, hyperlipidemia, and hypertension in high-fat diet-induced obese mice
Dohaekseunggi-tang (DHSGT) is a traditional plant-based medicine prescribed to promote blood circulation and to treat obesity and hypertension. The present study aimed to identify potential anti-obesity activi...
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Article
Open AccessGains of ubiquitylation sites in highly conserved proteins in the human lineage
Post-translational modification of lysine residues of specific proteins by ubiquitin modulates the degradation, localization, and activity of these target proteins. Here, we identified gains of ubiquitylation ...
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Article
Open AccessHuman-specific protein isoforms produced by novel splice sites in the human genome after the human-chimpanzee divergence
Evolution of splice sites is a well-known phenomenon that results in transcript diversity during human evolution. Many novel splice sites are derived from repetitive elements and may not contribute to protein ...
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Article
Bioconversion composition of Ssanghwa-tang fermented by Lactobacillus fermentum
Ssanghwa-tang is a medicinal formula that is widely prescribed in Korea to decrease fatigue after an illness. Fermented herbal medicines might be made more efficacious than conventional herbal medicines by inc...
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Article
A 2.7-kb Deletion in the Human NLRP10 Gene Exon 2 Occurred After the Human–Chimpanzee Divergence
NLRP10 is a member of the NLRP protein family, which is involved in inflammation and apoptosis. Genome sequence comparisons revealed that a 2.7-kb deletion occurred in the human NLRP10 gene exon 2 after the diver...
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Chapter and Conference Paper
Modelling of a Bubble Absorber in an Ammonia-Salt Absorption Refrigerator
In this study, a one-dimensional model is developed for a vertical bubble tube absorber based on the analogies between momentum, heat and mass transfers in a two-phase co-current upward flow. The model is comp...
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Article
Platelet-activating factor antagonistic activity and13C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis
In the course of searching for PAF receptor antagonists, pregomisin (1) and chamigrenal (2) were isolated from the fruits ofSchizandra chinensis Baill by the bioactivity-guided isolation. Both compounds showed PA...
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Article
Sesquiterpene components from the flower buds ofMagnolia fargesii
From the Chinese crude drugshin-i, the flower buds ofMagnolia fargesii, four sesquiterpene, oplopanone (1), oplodiol (2), homalomenol A (3) and 1β,4β,7α-trihydroxyeudesmane (4) were isolated. These structures wer...