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Article
Open AccessDEEPOMICS FFPE, a deep neural network model, identifies DNA sequencing artifacts from formalin fixed paraffin embedded tissue with high accuracy
Formalin-fixed, paraffin-embedded (FFPE) tissue specimens are routinely used in pathological diagnosis, but their large number of artifactual mutations complicate the evaluation of companion diagnostics and an...
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Article
Open AccessDetecting unregistered users through semi-supervised anomaly detection with similarity datasets
Recent research has focused on exploring systems that incorporate anomaly detection models to automate the addition of users in user recognition systems. Anomaly detection, a method used to distinguish between...
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Article
Open AccessThe conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
Termination of RNA polymerase II (Pol II) transcription is an important step in the transcription cycle, which involves the dislodgement of polymerase from DNA, leading to release of a functional transcript. R...
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Article
Cd2+ binds to Atx1 and affects the physical interaction between Atx1 and Ccc2 in Saccharomyces cerevisiae
The ATX1 deletion strain of Saccharomyces cerevisiae is more resistant to Cd2+ than the wild-type. To investigate the function of Atx1 in Cd2+ toxicity, we used a metal-binding assay to study the interaction betw...
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Article
FgEnd1 is a putative component of the endocytic machinery and mediates ferrichrome uptake in F. graminearum
The function of endocytic pathway in filamentous fungi has remained elusive. Recently, we have identified that FgEnd1, which has a 27% amino acid homology and shares specific EH3 domain with ScEnd3 of Saccharomyc...
