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1,118 Result(s)
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Article
Performance, kinetic characteristics and bacterial community of short-cut nitrification and denitrification system at different ferrous ion conditions
In order to explore the operation performance, kinetic characteristics and bacterial community of the short-cut nitrification and denitrification (SND) system, the SND system with pre-cultured short cut nitrif...
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Article
Effect of RANKL on Lower Depressive Symptoms In Hemodialysis Patients
Depression and osteoporosis are common diseases in dialysis patients. In addition, patients with osteoporosis are more susceptible to depression. Contrary to previous anti-osteoporosis agents, denosumab and ro...
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Article
Open AccessGenome-wide analysis of MYB transcription factor family and AsMYB1R subfamily contribution to ROS homeostasis regulation in Avena sativa under PEG-induced drought stress
The myeloblastosis (MYB) transcription factor (TF) family is one of the largest and most important TF families in plants, playing an important role in a life cycle and abiotic stress.
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Article
GSK621 ameliorates high glucose-induced renal injury by inducing autophagy via AMPK/ULK1 signaling pathway: an in vitro and in vivo study
Diabetic nephropathy (DN) could lead to renal failure and its morbidity is increasing throughout the world. The activation of AMP-activated protein kinase (AMPK) has been proven to play a protective role in ki...
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Article
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge
The EMDataResource Ligand Model Challenge aimed to assess the reliability and reproducibility of modeling ligands bound to protein and protein–nucleic acid complexes in cryogenic electron microscopy (cryo-EM) ...
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Article
CYTOR-NFAT1 feedback loop regulates epithelial-mesenchymal transition of retinal pigment epithelial cells
Epithelial mesenchymal transition (EMT) occurring in retinal pigment epithelial cells (RPE) is a crucial mechanism that contributes to the development of age-related macular degeneration (AMD), a pivotal facto...
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Article
Silybin attenuates avermectin-induced oxidative damage in carp respiration by modulating the cGAS-STING pathway and endoplasmic reticulum stress
Avermectin is a commonly used insect repellent for aquaculture and crops, but it is easy to remain in the aquatic environment, causing organism disorders, inflammation, and even death. This resulted in signifi...
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Article
Open AccessHippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity
Natural killer (NK) cells play a crucial role in immune response against viral infections and tumors. However, further investigation is needed to better understand the key molecules responsible for determining...
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Open AccessChromosome-level genome assembly provides insights into the genetic diversity, evolution, and flower development of Prunus conradinae
Prunus conradinae, a valuable flowering cherry belonging to the Rosaceae family subgenus Cerasus and endemic to China, has high economic and ornamental value. However, a high-quality P. conradinae genome is unava...
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Article
Development of Sugar Industry in China: R&D Priorities for Sustainable Sugarcane Production
This paper introduces the status of the sugar industry in China, especially the production of sugarcane, sugarbeet and sugar, as well as achievements in sugarcane breeding, farming technology exploitation and ...
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Article
Open AccessAlternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms
Dimethylsulfoniopropionate (DMSP) is an abundant marine organosulfur compound with roles in stress protection, chemotaxis, nutrient and sulfur cycling and climate regulation. Here we report the discovery of a ...
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Article
Open AccessStructural variant landscapes reveal convergent signatures of evolution in sheep and goats
Sheep and goats have undergone domestication and improvement to produce similar phenotypes, which have been greatly impacted by structural variants (SVs). Here, we report a high-quality chromosome-level refere...
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Article
Open AccessOliTag-seq enhances in cellulo detection of CRISPR-Cas9 off-targets
The potential for off-target mutations is a critical concern for the therapeutic application of CRISPR-Cas9 gene editing. Current detection methodologies, such as GUIDE-seq, exhibit limitations in oligonucleot...
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Article
Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity
It is said that a wide range of renal functions are at risk from arsenic exposure. We examined how lactoferrin administration may mitigate inflammation, apoptosis, redox imbalance, and fibrosis in order to cou...
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Article
Large-scale whole-exome sequencing of neuropsychiatric diseases and traits in 350,770 adults
While numerous genomic loci have been identified for neuropsychiatric conditions, the contribution of protein-coding variants has yet to be determined. Here we conducted a large-scale whole-exome-sequencing st...
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Article
Potential use of maize–peanut intercrop** to adapt to drought and nitrogen–shortage impacts
The objective of this study was to propose a maize–peanut intercrop** system for traditional sole maize to increase economic benefits and decrease environmental pollution for dryland farming.
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Article
Effects of exotic detritus input on native litter breakdown in a eutrophic lake: investigating the home-field advantage
Invasive plants have been shown to alter ecosystem functions. However, there is limited information available on the effect of the invasive species litter input on native litter decomposition and home-field ad...
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Effects of future climate change on rare and endangered species in inner Mongolia, China: Vulnerability, priority conservation areas and sustainable conservation strategies
Rare and endangered species have narrow geographical distributions and are vulnerable to environmental changes. Studying the impact of future climate change on their distributions and identifying areas of high...
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Mechanisms for improving the quality of crucian carp (Carassius auratus) by short-term low-salinity treatment revealed by UPLC-MS and GC–MS
Due to high-density farming methods and poor farming environments, freshwater fish often have poor muscle texture and a fishy odor before marketing, which impacts consumer acceptance. Short-term low-salinity s...
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Article
Open AccessGenome characterisation and comparative analysis of Schaalia dentiphila sp. nov. and its subspecies, S. dentiphila subsp. denticola subsp. nov., from the human oral cavity
Schaalia species are primarily found among the oral microbiota of humans and other animals. They have been associated with various infections through their involvement in biofilm formation, modulation of host res...