5 Result(s)
within
Dong Kun Lee
Biomedicine
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Article
PTPN6 regulates the cell-surface expression of TRPM4 channels in HEK293 cells
Transient receptor-potential, cation channel, subfamily M, member 4 (TRPM4) channels regulate a variety of physiological and pathological processes; however, their roles as functional channels under diverse co...
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Article
Dopamine D4 receptors linked to protein kinase G are required for changes in dopamine release followed by locomotor activity after repeated cocaine administration
We previously found that the dopamine D2-type receptors (D2 and D3 receptors), coupled to protein kinase G (PKG), upregulate locomotor activity after repeated cocaine administration. In this study, D4 receptor...
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Article
Open AccessAn Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells
One in eight women will be affected by breast cancer in her lifetime. Approximately 75% of breast cancers express estrogen receptor alpha (ERα) and/or progesterone receptor and these receptors are markers for ...
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Article
Protein Kinase G Regulates Dopamine Release, ΔFosB Expression, and Locomotor Activity After Repeated Cocaine Administration: Involvement of Dopamine D2 Receptors
Protein kinase G (PKG) activation has been implicated in the regulation of synaptic plasticity in the brain. This study was conducted to determine the involvement of PKG-associated dopamine D2 (D2) receptors i...
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Article
Repeated cocaine administration increases nitric oxide efflux in the rat dorsal striatum
Repeated injections of cocaine alter extracellular nitric oxide (NO) efflux via interactions between dopamine and glutamate receptor-coupled signaling cascades.
