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  1. No Access

    Article

    It’s not all equal: a multiphasic theory of thymic involution

    Regression of the thymus is a key feature of immunosenescence, which coincides with a decrease in T cell output and contributes to the restriction of the T cell repertoire in the elderly, leading to increased ...

    Danielle Aw, Donald B. Palmer in Biogerontology (2012)

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    Article

    Phenotypical and morphological changes in the thymic microenvironment from ageing mice

    The thymus is crucial for T-cell output and the age-associated involution of this organ, is thought to have a major impact in the decline in immunity that is seen in later life. The mechanism that underlines t...

    Danielle Aw, Frances Taylor-Brown, Kate Cooper, Donald B. Palmer in Biogerontology (2009)

  3. No Access

    Article

    Characterization of a recent retroposon insertion on mouse Chromosome 2 and localization of the cognate parental gene to Chromosome 11

    The genomic sequence on mouse Chromosome (Chr) 2 corresponding to a previously identified novel cDNA has been characterized. The genomic organization of this locus, adjacent to the beta 2 microglobulin gene, h...

    Donald B. Palmer, John H. McVey, Reshma Purohit, Jean Picard… in Mammalian Genome (1998)