Skip to main content

and
  1. No Access

    Article

    Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit

    The authors use transgenic mice to show that zinc modulates NMDA receptors containing the NR2A subunit, and that this interaction influences pain control in vivo.

    Chihiro Nozaki, Angela Maria Vergnano, Dominique Filliol in Nature Neuroscience (2011)

  2. No Access

    Article

    Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses

    The role of the opioid system in controlling pain1, reward and addiction2,3 is well established, but its role in regulating other emotional responses is poorly documented in pharmacology4. The μ-, δ- and κ- opioi...

    Dominique Filliol, Sandy Ghozland, Johanna Chluba, Miguel Martin in Nature Genetics (2000)