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    Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit

    The authors use transgenic mice to show that zinc modulates NMDA receptors containing the NR2A subunit, and that this interaction influences pain control in vivo.

    Chihiro Nozaki, Angela Maria Vergnano, Dominique Filliol… in Nature Neuroscience (2011)