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  1. Article

    Circulating tumour DNA — looking beyond the blood

    Over the past decade, various liquid biopsy techniques have emerged as viable alternatives to the analysis of traditional tissue biopsy samples. Such surrogate ‘biopsies’ offer numerous advantages, including t...

    Ann Tivey, Matt Church, Dominic Rothwell, Caroline Dive… in Nature Reviews Clinical Oncology (2022)

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  2. Article

    Open Access

    Circulating Tumour DNA in Melanoma—Clinic Ready?

    Liquid biopsies, including circulating tumour DNA (ctDNA), can inform a variety of clinical questions. This review examines the potential role of ctDNA as a clinical tool to inform clinical decision-making fro...

    Ann Tivey, Fiona Britton, Julie-Ann Scott, Dominic Rothwell… in Current Oncology Reports (2022)

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  3. Article

    Open Access

    First generation anti-CD19 chimeric antigen receptor-modified T cells for management of B cell malignances: initial analysis of an ongoing Phase I clinical trial

    Manon Evans, Ryan Guest, Dominic Rothwell… in Journal for ImmunoTherapy of Cancer (2014)

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  4. No Access

    Article

    Genomic characterization of the chromosomal breakpoints of t(4;14) of multiple myeloma suggests more than one possible aetiological mechanism

    Using FISH-based techniques, rearrangements of the immunoglobulin heavy-chain (IgH) locus at 14q32 have been found in the majority of cases of multiple myeloma (MM). Some of these IgH translocations are recurr...

    James A L Fenton, Guy Pratt, Andy C Rawstron, Kathryn Sibley, Dominic Rothwell… in Oncogene (2003)