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Article
Open AccessMultiscale mechanical characterisation of the craniofacial system under external forces
Premature fusion of craniofacial joints, i.e. sutures, is a major clinical condition. This condition affects children and often requires numerous invasive surgeries to correct. Minimally invasive external load...
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Article
Open AccessA review of pre-hospital extracorporeal cardiopulmonary resuscitation and its potential application in the North East of England
Patients in the UK who suffer an out-of-hospital cardiac arrest are treated with cardiopulmonary resuscitation in the pre-hospital environment. Current survival outcomes are low in out-of-hospital cardiac arre...
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Article
Open AccessMechanical loading of cranial joints minimizes the craniofacial phenotype in Crouzon syndrome
Children with syndromic forms of craniosynostosis undergo a plethora of surgical interventions to resolve the clinical features caused by the premature fusion of cranial sutures. While surgical correction is r...
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Article
Open AccessAurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer
Androgen receptor variants (AR-Vs) provide a mechanism of therapy evasion in castrate-resistant prostate cancer (CRPC), yet mechanisms of regulation remain largely unknown. Here we investigate the role of Auro...
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Chapter
Linking Localisation and Language Resources
Industrial localisation is changing from the periodic translation of large bodies of content to a long-tail of small, heterogeneous translations processed in an agile and demand-driven manner. Software localis...
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Article
Open AccessAnalysis of multiple single nucleotide polymorphisms closely positioned in the ovine PRNPgene using linear fluorescent probes and melting curve analysis
Resistance and susceptibility to scrapie has been associated with single nucleotide polymorphisms located within codons 136, 154 and 171 of the ovine prion protein gene (PRNP). Dual-labelled HyBeacon probes were ...
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Chapter and Conference Paper
Improving Scalability in Pub-Sub Knowledge-Based Networking by Semantic Clustering
The three main pub/sub systems – type-based, content-based and topic-based networks allow for normalised subscriptions and publications using a combination of push/pull message delivery. Knowledge-based Networ...
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Chapter
A Tool for Inference Detection and Knowledge Discovery in Databases
Latent dependencies and relationships between groups of attributes in databases can produce inference channels that pose serious security threats. This paper uses a powerful knowledge discovery formalism for m...
