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Article
Open AccessA deep dive into burn-mediated ARDS severity assessment: a retrospective study on hematological markers
Acute Respiratory Distress Syndrome (ARDS) is a critical form of Acute Lung Injury (ALI), challenging clinical diagnosis and severity assessment. This study evaluates the potential utility of various hematolog...
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Article
Open AccessBig data insights into the diagnostic values of CBC parameters for sepsis and septic shock in burn patients: a retrospective study
Sepsis and septic shock are prevalent and life-threatening complications in burn patients. Despite their severity, existing diagnostic methods are limited. This study aims to evaluate the efficacy of Complete ...
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Article
Open AccessPioneering predictions of AKI and AKIN severity in burn patients: a comprehensive CBC approach
This study aims to evaluate the utility of complete blood count (CBC) markers, in conjunction with the acute kidney injury network (AKIN) criteria, for the early detection, severity assessment, and prediction ...
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Article
Open AccessTracking longitudinal biomarkers in burn patients with sepsis and acute kidney injury: an unsupervised clustering approach
Sepsis is a grave medical disorder characterized by a systemic inflammatory response to infection. Furthermore, it is a leading cause of morbidity and mortality, especially in hospitalized patients. Acute kidn...
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Article
Open AccessEvaluating clinical heterogeneity and predicting mortality in severely burned patients through unsupervised clustering and latent class analysis
Burn injuries often result in a high level of clinical heterogeneity and poor prognosis in patients with severe burns. Clustering algorithms, which are unsupervised methods that can identify groups with simila...
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Article
Open AccessTime-varying discrimination accuracy of longitudinal biomarkers for the prediction of mortality compared to assessment at fixed time point in severe burns patients
The progression of biomarkers over time is considered an indicator of disease progression and helps in the early detection of disease, thereby reducing disease-related mortality. Their ability to predict outco...
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Article
Open AccessTrajectories of longitudinal biomarkers for mortality in severely burned patients
This study aimed to investigate the differences in the trajectory of blood biomarkers routinely assessed through forward- and backward-looking approaches among burn patients. This cohort study included patient...
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Article
Clinical Outcome of Cryopreserved Acellular Dermal Matrix for Full-Thickness Burns
This study aimed at identifying properties of cryopreserved acellular dermal matrix (CPADM) and evaluating its effectiveness in the treatment of burn patients. The prospective study included 50 patients who re...
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Article
Open AccessAssessment of biochemical markers in the early post-burn period for predicting acute kidney injury and mortality in patients with major burn injury: comparison of serum creatinine, serum cystatin-C, plasma and urine neutrophil gelatinase-associated lipocalin
The reported mortality rates range from 28% to 100% in burn patients who develop acute kidney injury (AKI) and from 50% to 100% among such patients treated with renal replacement therapy. Recently, the serum c...
