5 Result(s)
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Article
The Notch repressor complex in Drosophila: in vivo analysis of Hairless mutants using overexpression experiments
During development of higher animals, the Notch signalling pathway governs cell type specification by mediating appropriate gene expression responses. In the absence of signalling, Notch target genes are silen...
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Article
Conservation of the Notch antagonist Hairless in arthropods: functional analysis of the crustacean Daphnia pulex Hairless gene
The Notch signaling pathway is highly conserved in all animal metazoa: upon Notch receptor activation, transcription of Notch target genes is turned on by an activator complex that centers on the transcription...
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Article
Open AccessProtein Kinase D regulates several aspects of development in Drosophila melanogaster
Protein Kinase D (PKD) is an effector of diacylglycerol-regulated signaling pathways. Three isoforms are known in mammals that have been linked to diverse cellular functions including regulation of cell prolif...
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Article
Green fluorescent protein as a convenient and versatile marker for studies on functional genomics in Drosophila
Gene function can be deduced from lack or gain of activity. For the manipulation of gene doses or activity in Drosophila, a set of P-based vectors was constructed containing green fluorescent protein as marker. ...
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Article
Structure and regulation of the fushi tarazu gene from Drosophila hydei
The Drosophila melanogaster segmentation gene fushi tarazu (ftz) encodes a homeodomain-type transcription factor involved in the control of larval pattern formation. Loss of function mutations cause an embryonic ...
