5 Result(s)
within
Dieter Maier
Bioinformatics
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Article
Open AccessFrom comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration
Deep mining of healthcare data has provided maps of comorbidity relationships between diseases. In parallel, integrative multi-omics investigations have generated high-resolution molecular maps of putative rel...
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Article
Open AccessChainRank, a chain prioritisation method for contextualisation of biological networks
Advances in high throughput technologies and growth of biomedical knowledge have contributed to an exponential increase in associative data. These data can be represented in the form of complex networks of bio...
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Article
Open AccessImplementing systems medicine within healthcare
The cause of a complex disease cannot be pinpointed to a single origin; rather, a highly complex network of many factors that interact on different levels over time and space is disturbed. This complexity requ...
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Article
Open AccessData integration in the era of omics: current and future challenges
To integrate heterogeneous and large omics data constitutes not only a conceptual challenge but a practical hurdle in the daily analysis of omics data. With the rise of novel omics technologies and through lar...
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Article
Open AccessKnowledge management for systems biology a general and visually driven framework applied to translational medicine
To enhance our understanding of complex biological systems like diseases we need to put all of the available data into context and use this to detect relations, pattern and rules which allow predictive hypothe...
