4 Result(s)
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Diba Ahmadi Rastegar
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Article
Open AccessPrediction of motor and non-motor Parkinson’s disease symptoms using serum lipidomics and machine learning: a 2-year study
Identifying biological factors which contribute to the clinical progression of heterogeneous motor and non-motor phenotypes in Parkinson’s disease may help to better understand the disease process. Several lip...
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Article
Open AccessSingle-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion
DNA methylation is a critical molecular mark involved in cellular differentiation and cell-specific processes. Single-cell whole genome DNA methylation profiling methods hold great potential to resolve the DNA...
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Article
Open AccessEffect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages
Leucine-rich-repeat kinase 2 (LRRK2), a potential therapeutic target for the treatment of Parkinson’s disease (PD), is highly expressed in monocytes and macrophages and may play a role in the regulation of inf...
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Article
Open AccessParkinson’s progression prediction using machine learning and serum cytokines
The heterogeneous nature of Parkinson’s disease (PD) symptoms and variability in their progression complicates patient treatment and interpretation of clinical trials. Consequently, there is much interest in d...
