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  1. Article

    Open Access

    PD-L1 and PD-L2 expression correlated genes in non-small-cell lung cancer

    Programmed cell death ligand-1 (PD-L1) and ligand-2 (PD-L2) interaction with programmed cell death protein-1 (PD-1) represent an immune-inhibiting checkpoint mediating immune evasion and is, accordingly, an im...

    Trine Vilsbøll Larsen, Dianna Hussmann, Anders Lade Nielsen in Cancer Communications (2019)

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  2. No Access

    Protocol

    Methylation-Sensitive High Resolution Melting (MS-HRM)

    Methylation-Sensitive High Resolution Melting (MS-HRM) is an in-tube, PCR-based method to detect methylation levels at specific loci of interest. A unique primer design facilitates a high sensitivity of the as...

    Dianna Hussmann, Lise Lotte Hansen in DNA Methylation Protocols (2018)

  3. No Access

    Article

    Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system

    Programmable DNA nucleases such as TALENs and CRISPR/Cas9 are emerging as powerful tools for genome editing. Dual-fluorescent surrogate systems have been demonstrated by several studies to recapitulate DNA nuc...

    Yan Zhou, Yong Liu, Dianna Hussmann, Peter Brøgger… in Cellular and Molecular Life Sciences (2016)