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503 Result(s)
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Article
A train bearing imbalanced fault diagnosis method based on extended CCR and multi-scale feature fusion network
The number of fault samples is much less than the normal samples in the actual operation of the train bearing, and the imbalanced characteristics of the fault data significantly decrease the performance of the...
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Article
Gastric Cancer Mesenchymal Stem Cells Trigger Endothelial Cell Functional Changes to Promote Cancer Progression
Our previous studies have highlighted the pivotal role of gastric cancer mesenchymal stem cells (GCMSCs) in tumor initiation, progression, and metastasis. In parallel, it is well-documented that endothelial ce...
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Analyzing the Role of Changing Climate on the Variability of Intensity-Duration-Frequency Curve Using Wavelet Analysis
Climate change has significantly influenced the occurrence of extreme events and their outcomes in develo** countries, like Pakistan. This research investigates the impact of climate variability on the devel...
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Open AccessVaccination intentions of hypertensive Chinese individuals during the COVID-19 epidemic: a structural equation modeling study
Given the high prevalence of hypertension among Chinese adults, this population is at a significantly increased risk of severe COVID-19 complications. The purpose of this study is to assess the willingness of ...
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Article
Open AccessExploring plant-derived phytochrome chaperone proteins for light-switchable transcriptional regulation in mammals
Synthetic biology applications require finely tuned gene expression, often mediated by synthetic transcription factors (sTFs) compatible with the human genome and transcriptional regulation mechanisms. While v...
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Article
Task-like training paradigm in CLIP for zero-shot sketch-based image retrieval
The Contrastive Language-Image Pre-training model (CLIP) has recently gained attention in the zero-shot domain. However it still falls short in addressing cross-modal perception, and the semantic gap between s...
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Article
Communication-efficient clustered federated learning via model distance
Clustered Federated Learning (CFL) leverages the differences among data distributions on clients to partition all clients into several clusters for personalized federated training. Compared with the convention...
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Article
Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis
Sphingomyelin (SM) has key roles in modulating mammalian membrane properties and serves as an important pool for bioactive molecules. SM biosynthesis is mediated by the sphingomyelin synthase (SMS) family, com...
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Article
Open AccessStructural basis of a small monomeric Clivia fluorogenic RNA with a large Stokes shift
RNA-based fluorogenic modules have revolutionized the spatiotemporal localization of RNA molecules. Recently, a fluorophore named 5-((Z)-4-((2-hydroxyethyl)(methyl)amino)benzylidene)-3-methyl-2-((E)-styryl)-3,5-d...
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Article
Open AccessEndocardial HDAC3 is required for myocardial trabeculation
Failure of proper ventricular trabeculation is often associated with congenital heart disease. Support from endocardial cells, including the secretion of extracellular matrix and growth factors is critical for...
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Open AccessCorrection: Pancancer analysis of the prognostic and immunological role of FANCD2: a potential target for carcinogenesis and survival
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Article
Research on an innovative structure of an open-ribbed steel–ultra-high performance concrete composite bridge deck
To completely solve the problem of fatigue cracking issue of orthotropic steel bridge decks (OSDs), the authors proposed a steel–ultra-high performance concrete (UHPC) lightweight composite deck (LWCD) with cl...
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Open AccessEmergence of a clinical Salmonella enterica serovar 1,4,[5], 12: i:-isolate, ST3606, in China with susceptibility decrease to ceftazidime-avibactam carrying a novel blaCTX-M-261 variant and a blaNDM-5
The detection rate of Salmonella enterica serovar 1,4,[5], 12: i: - (S. 1,4,[5], 12: i: -) has increased as the most common serotype globally. A S. 1,4,[5], 12: i: - strain named ST3606 (sequence type 34), isolat...
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Article
Catalyzing oxygen reduction reaction with a worm-like oxide Ca3Co2O6 in solid-oxide fuel cells
A worm-like oxide Ca3Co2O6 was prepared by electrostatic spinning as a cathode material for solid-oxide fuel cells. Compared to the plain granular structure, the worm-like Ca3Co2O6 exhibits a desirable morphologi...
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Open AccessReconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic l-threonine producing Corynebacterium glutamicum
l-Threonine is an important feed additive with the third largest market size among the amino acids produced by microbial fermentation. The GRAS (generally regarded as safe) industrial workhorse Corynebacterium gl...
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Article
Efficient Tool Wear Prediction in Manufacturing: BiLPReS Hybrid Model with Performer Encoder
Predictive maintenance in industrial settings, especially tool wear prediction, remains crucial for operational efficiency and cost reduction. This paper proposes BiLPReS, a novel predictive model leveraging a...
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Article
Open AccessMerit of integrating in situ transcriptomics and anatomical information for cell annotation and lineage construction in single-cell analyses of Populus
Cell type annotation and lineage construction are two of the most critical tasks conducted in the analyses of single-cell RNA sequencing (scRNA-seq). Four recent scRNA-seq studies of differentiating xylem prop...
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Article
Retraction Note: Two Mixed Ligand Coordination Polymers: Selective Detection of TNP and Protective Effect on Alzheimer’s Disease by Stimulating Cell Autophagy
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Article
A programmable protease-based protein secretion platform for therapeutic applications
Cell-based therapies represent potent enabling technologies in biomedical science. However, current genetic control systems for engineered-cell therapies are predominantly based on the transcription or transla...
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A framework for risk assessment of groundwater contamination integrating hydrochemical, hydrogeological, and electrical resistivity tomography method
Groundwater contamination have been widely concerned. To reliably conduct risk assessment, it is essential to accurately delineate the contaminant distribution and hydrogeological condition. Electrical resisti...