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Article
Open AccessLncRNA HOTAIR down-expression inhibits the invasion and tumorigenicity of epithelial ovarian cancer cells by suppressing TGF-β1 and ZEB1
Epithelial ovarian cancer (EOC) is a pathological type with a higher mortality rate among gynecological cancers today. Long-chain noncoding RNAs (lncRNAs) can regulate the transcription and expression of cellu...
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Article
Effect of torrefaction on the pyrolysis behavior, kinetics, and phenolic products of lignin
Torrefaction is a process of mild pyrolysis at 200–300 °C under nitrogen atmosphere and has been considered to be an effective way to improve the properties of biomass. In this study, lignin was subjected to t...
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Article
Upgrading of biomass pellets by torrefaction and its influence on the hydrophobicity, mechanical property, and fuel quality
In this study, soybean straw pellets (SSP) and pine wood pellets (PWP) were used as materials for torrefaction at 200–350 °C. Impacts of torrefaction temperature on the physicochemical properties, hydrophobici...
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Article
Open AccessStudy on antibiotic susceptibility of Salmonella typhimurium L forms to the third and forth generation cephalosporins
Salmonella typhimurium is a pathogenic gram-negative bacterium, which is found primarily in the intestinal lumen. It often causes diarrhea in infants and young children and leads to food poisoning. Drug resistanc...
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Article
Preparation and thermostability of cellulose nanocrystals and nanofibrils from two sources of biomass: rice straw and poplar wood
Two types of nanocellulose (cellulose nanocrystals—CNCs and cellulose nanofibrils—CNFs) were isolated from two biomass resources. The morphology, crystallinity and thermal stability of the nanocelluloses were ...
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Article
Open AccessDownregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition
Emerging evidence indicates that dysregulated long intervening non-coding RNA (lincRNA) HOTAIR correlates highly with tumor invasion and metastasis but a link between the high expression of HOTAIR and the meta...
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Article
Open AccessGene therapy of ovarian cancer using IL-21-secreting human umbilical cord mesenchymal stem cells in nude mice
The human umbilical cord mesenchymal stem cells (hUCMSCs) have the ability to migrate into tumors and therefore have been considered as an alternative source of mesenchymal progenitors for the therapy of malig...
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Article
Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells
Studies from hematopoietic origin malignancies have demonstrated that multiple myeloma contain a rare population of cancer stem cells (CSCs) that are responsible for tumor multiresistance and recurrence. The g...
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Article
Fe3O4 nanoparticle loaded paclitaxel induce multiple myeloma apoptosis by cell cycle arrest and increase cleavage of caspases in vitro
Multiple myeloma (MM) still remains an incurable disease in spite of extending the patient survival by new therapies. The hypothesis of cancer stem cells (CSCs) states that although chemotherapy kills most tum...
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Article
Open AccessMicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117+CD44+ ovarian cancer stem cells by regulating epithelial-mesenchymal transition
Cancer stem cells (CSCs) are believed to be ‘seed cell’ in cancer recurrence and metastasis. MicroRNAs (miRNAs) can play an important role in the progression of primary tumor towards metastasis by regulating t...
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Article
Open AccessEvaluation of characteristics of CD44+CD117+ ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures
Cancer stem cells (CSCs) are thought to be capable of surviving conventional chemotherapeutic treatments because the cells have more resistant to anticancer drugs than common cancer cells. Most in vitro studies i...
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Article
TG-DSC method applied to drying characteristics and heat requirement of cotton stalk during drying
Drying characteristics of cotton stalk were investigated at four temperatures (60, 80, 100 and 120 °C) using a simultaneous thermal analyzer (TG-DSC). Heat requirements of cotton stalk during drying were calcu...
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Article
Antitumor efficacy of viable tumor vaccine modified by heterogenetic ESAT-6 antigen and cytokine IL-21 in melanomatous mouse
The goal of this study was to investigate whether glycosylphosphatidylinositol (GPI)-anchored 6 kDa early secreted antigenic target (ESAT-6) and IL-21-producing B16F10/ESAT-6-GPI-IL-21 viable vaccine would ind...
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Article
On-line catalytic upgrading of biomass fast pyrolysis products
Pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) was employed to achieve fast pyrolysis of biomass and on-line analysis of the pyrolysis vapors. Four biomass materials (poplar wood, fir wood, cotton s...