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  1. Article

    Open Access

    Med1 inhibits ferroptosis and alleviates liver injury in acute liver failure via Nrf2 activation

    Extensive hepatocyte mortality and the absence of specific medical therapy significantly contribute to the unfavorable prognosis of acute liver failure (ALF). Ferroptosis is a crucial form of cell death involv...

    Zi-Ying Lei, Zhi-Hui Li, Deng-Na Lin, **g Cao, Jun-Feng Chen in Cell & Bioscience (2024)

  2. No Access

    Article

    Safety and efficacy of Thymosin α1 in the treatment of hepatitis B virus-related acute-on-chronic liver failure: a randomized controlled trial

    Mortality from hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) is high. Severe infection is the most important complication that affects the outcomes of ACLF patients. Thymosin α1 (Tα1) c...

    Jun-feng Chen, Shu-ru Chen, Zi-ying Lei, Hui-juan Cao in Hepatology International (2022)

  3. Article

    Open Access

    The impact of serum thyroid-stimulation hormone levels on the outcome of hepatitis B virus related acute-on-chronic liver failure: an observational study

    Thyroid dysfunction has been reported in severe liver diseases. The aim of this study was to analyze the impact of serum thyroid-stimulation hormone (TSH) levels on the prognosis of patients with hepatitis B v...

    Jun-feng Chen, Wei-zhen Weng, Miao Huang, **ao-hua Peng, **g Zhang in BMC Gastroenterology (2022)