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    Article

    STT3A-mediated viral N-glycosylation underlies the tumor selectivity of oncolytic virus M1

    Oncolytic viruses are emerging as promising anticancer agents. Although the essential biological function of N-glycosylation on viruses are widely accepted, roles of N-glycan and glycan-processing enzyme in on...

    Deli Song, Xudong Jia, Yuanzhu Gao, Tong **ao, Jia Dan, Runling Shen, **g Cai in Oncogene (2023)

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    Article

    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC

    Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype among breast tumors and remains a challenge even for the most current therapeutic regimes. Here, we demonstrate that oncolytic alph...

    Jiayu Zhang, Ying Liu, **gyi Tan, Yanming Zhang, Chun-Wa Wong, Ziqing Lin in Oncogene (2021)