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    Article

    Cell-type-specific labeling and profiling of glycans in living mice

    Metabolic labeling of glycans with clickable unnatural sugars has enabled glycan analysis in multicellular systems. However, cell-type-specific labeling of glycans in vivo remains challenging. Here we develop ...

    **nqi Fan, Qitao Song, De-en Sun, Yi Hao, **gyang Wang in Nature Chemical Biology (2022)

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    Article

    Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy

    A main determinant of the spatial resolution of live-cell super-resolution (SR) microscopes is the maximum photon flux that can be collected. To further increase the effective resolution for a given photon flu...

    Weisong Zhao, Shiqun Zhao, Liuju Li, **aoshuai Huang, Shijia **ng in Nature Biotechnology (2022)

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    Article

    Click-ExM enables expansion microscopy for all biomolecules

    Expansion microscopy (ExM) allows super-resolution imaging on conventional fluorescence microscopes, but has been limited to proteins and nucleic acids. Here we develop click-ExM, which integrates click labeli...

    De-en Sun, **nqi Fan, Yujie Shi, Hao Zhang, Zhimin Huang, Bo Cheng in Nature Methods (2021)

  4. Article

    Open Access

    Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells

    Unnatural monosaccharides such as azidosugars that can be metabolically incorporated into cellular glycans are currently used as a major tool for glycan imaging and glycoproteomic profiling. As a common practi...

    Yi Hao, **nqi Fan, Yujie Shi, Che Zhang, De-en Sun, Ke Qin in Nature Communications (2019)

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    Article

    A security-based steganographic scheme in vector quantization coding between correlated neighboring blocks

    With the growth of the Internet and the advancements in modern communication systems, sending data over the Internet or other media is now a commonplace practice. Consequently, it has become an important issue...

    Cheng-Ta Huang, Li-Chiun Lin, De-En Sun in Multimedia Tools and Applications (2019)

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    Chapter and Conference Paper

    VQ Coding in Data Hiding Using Correlated Neighboring Blocks in Security Performance

    With the continued expansion of the Internet and increased means of communication, it is inevitable that we send data via the Internet or other such media. The important issue of maintaining the confidentialit...

    Cheng-Ta Huang, De-En Sun, Yen-Lin Chen in Intelligence and Security Informatics (2017)

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    Article

    Silicon Strengthened CrAlVN Coatings

    CrAlVN coatings are of good intrinsic mechanical and tribological properties but lack of strength. Silicon can provide nitride coating high strength and excellent oxidation resistance. Logically, the combinati...

    Qiang Li, Yue-xiu Qiu, Bo Li in Journal of Iron and Steel Research Interna… (2015)