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Article
Metabolomics reveals synergy between Ag and g-C3N4 in Ag/g-C3N4 composite photocatalysts: a unique feature among Ag-doped biocidal materials
The silver/graphitic carbon nitride (Ag/g-C3N4) composite system exerts biocidal activity against the pathogenic bacterium Escherichia coli 1337-H that is stronger than that of well-known silver and titanium oxid...
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Article
Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Enzyme engineering has allowed not only the de novo creation of active sites catalysing known biological reactions with rates close to diffusion limits, but also the generation of abiological sites performing ...
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Protocol
Metabolomics Analysis of Leishmania by Capillary Electrophoresis and Mass Spectrometry
Capillary electrophoresis coupled to mass spectrometry is an analytical platform ideal for the analysis of ionic or polar metabolites. It constitutes a perfect complement to reversed-phase liquid chromatograph...
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Article
Open AccessCanine Trypanosoma cruzi infection in the Bolivian Chaco
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo,...
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Chapter
Metabolomic-Based Methods in Diagnosis and Monitoring Infection Progression
A robust biomarker screening and validation is crucial for overcoming the current limits in the clinical management of infectious diseases. In this chapter, a general workflow for metabolomics is summarized. S...
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Article
Open AccessMetabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT
Ferroplasmaceae represent ubiquitous iron-oxidising extreme acidophiles with a number of unique physiological traits. In a genome-based study of Ferroplasma acidiphilum YT, the only speci...
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Article
Insights into the degradation capacities of Amycolatopsis tucumanensis DSM 45259 guided by microarray data
The analysis of catabolic capacities of microorganisms is currently often achieved by cultivation approaches and by the analysis of genomic or metagenomic datasets. Recently, a microarray system designed from ...
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Article
Open AccessHIV infection results in metabolic alterations in the gut microbiota different from those induced by other diseases
Imbalances in gut bacteria have been associated with multiple diseases. However, whether there are disease-specific changes in gut microbial metabolism remains unknown. Here, we demonstrate that human immunode...
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Article
Open AccessBacterial population and biodegradation potential in chronically crude oil-contaminated marine sediments are strongly linked to temperature
Two of the largest crude oil-polluted areas in the world are the semi-enclosed Mediterranean and Red Seas, but the effect of chronic pollution remains incompletely understood on a large scale. We compared the ...
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Article
Open AccessRanking the impact of human health disorders on gut metabolism: Systemic lupus erythematosus and obesity as study cases
Multiple factors have been shown to alter intestinal microbial diversity. It remains to be seen, however, how multiple collective pressures impact the activity in the gut environment and which, if any, is posi...
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Article
Open AccessUnderstanding the antimicrobial mechanism of TiO2-based nanocomposite films in a pathogenic bacterium
Titania (TiO2)-based nanocomposites subjected to light excitation are remarkably effective in eliciting microbial death. However, the mechanism by which these materials induce microbial death and the effects that...
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Article
Open AccessMicrobial life in the Lake Medee, the largest deep-sea salt-saturated formation
Deep-sea hypersaline anoxic lakes (DHALs) of the Eastern Mediterranean represent some of the most hostile environments on our planet. We investigated microbial life in the recently discovered Lake Medee, the larg...
