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    Article

    A bottom-up approach to gene regulation

    The ability to construct synthetic gene networks enables experimental investigations of deliberately simplified systems that can be compared to qualitative and quantitative models1,2,3,4,5,6,7,8,9,10,11,12,13,14,

    Nicholas J. Guido, **ao Wang, David Adalsteinsson, David McMillen, Jeff Hasty in Nature (2006)

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    Open Access

    Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks

    Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true for pathways that involve transcriptional ...

    David Adalsteinsson, David McMillen, Timothy C Elston in BMC Bioinformatics (2004)

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    Article

    Noise-Stabilized Long-Distance Synchronization in Populations of Model Neurons

    Rhythmic, synchronous firing of groups of neurons is associated with behaviorally relevant states, and it is thus of interest to understand the mechanisms by which synchronization may be achieved. In hippocamp...

    David McMillen, Nancy Kopell in Journal of Computational Neuroscience (2003)

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    Article

    Engineered gene circuits

    A central focus of postgenomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble comp...

    Jeff Hasty, David McMillen, J. J. Collins in Nature (2002)

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    Article

    Computational studies of gene regulatory networks: in numero molecular biology

  6. Post-genomic research will involve analysing the dynamics of gene regulation.

  7. Recent advances are making...

  8. Jeff Hasty, David McMillen, Farren Isaacs, James J. Collins in Nature Reviews Genetics (2001)

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    Chapter

    The ECESIS Economic-Demographic Model of the United States

    ECESIS is an interregional economic-demographic model of the United States. It consists of 51 regional econometric models (one for each state and the District of Columbia) and a multiregional demographic model...

    Paul Beaumont, Andrew Isserman in Population Change and the Economy: Social … (1986)