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    Article

    Structural basis of the acyl-transfer mechanism of human GPAT1

    Glycerol-3-phosphate acyltransferase (GPAT)1 is a mitochondrial outer membrane protein that catalyzes the first step of de novo glycerolipid biosynthesis. Hepatic expression of GPAT1 is linked to liver fat acc...

    Zachary Lee Johnson, Mark Ammirati… in Nature Structural & Molecular Biology (2023)

  2. Article

    Open Access

    Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20

    Chemokines are important protein-signaling molecules that regulate various immune responses by activating chemokine receptors which belong to the G protein-coupled receptor (GPCR) superfamily. Despite the subs...

    David Jonathan Wasilko, Zachary Lee Johnson, Mark Ammirati, Ye Che… in Nature Communications (2020)

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