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  1. Article

    Open Access

    Genomic adaptations of Campylobacter jejuni to long-term human colonization

    Campylobacter is a genus of bacteria that has been isolated from the gastrointestinal tract of humans and animals, and the environments they inhabit around the world. Campylobacter adapt to new environments by ch...

    Samuel J. Bloomfield, Anne C. Midwinter, Patrick J. Biggs, Nigel P. French in Gut Pathogens (2021)

  2. Article

    Open Access

    The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation

    The bacterial flagellum is a remarkable molecular motor, whose primary function in bacteria is to facilitate motility through the rotation of a filament protruding from the bacterial cell. A cap complex, consi...

    Natalie S. Al-Otaibi, Aidan J. Taylor, Daniel P. Farrell in Nature Communications (2020)

  3. Article

    Open Access

    Extra Territorial Excursions by European badgers are not limited by age, sex or season

    European badgers (Meles meles) in medium and high density populations show strong territorial behaviour. Territories in these populations are contiguous, well-marked and often unchanging over many years. Howev...

    David J. Kelly, Aoibheann Gaughran, Enda Mullen, Teresa MacWhite in Scientific Reports (2020)

  4. Article

    Open Access

    Bacterial periplasmic nitrate and trimethylamine-N-oxide respiration coupled to menaquinol-cytochrome c reductase (Qcr): Implications for electrogenic reduction of alternative electron acceptors

    The periplasmic reduction of the electron acceptors nitrate (Em +420 mV) and trimethylamine-N-oxide (TMAO; Em +130 mV) by Nap and Tor reductases is widespread in Gram-negative bacteria and is usually considered t...

    Nitanshu Garg, Aidan J. Taylor, David J. Kelly in Scientific Reports (2018)

  5. No Access

    Chapter

    Indicators of Ecological Integrity

    Freshwater Ecological Integrity (EI) incorporates the concepts of ecosystem “health”, unimpaired structure, composition and function and a capacity for self-renewal and, as such, it is a holistic advance over ...

    Marc Schallenberg, Mary D. de Winton, David J. Kelly in Lake Restoration Handbook (2018)

  6. No Access

    Protocol

    Metabolomic Analysis of Campylobacter jejuni by Direct-Injection Electrospray Ionization Mass Spectrometry

    Direct-injection mass spectrometry (DIMS) is a means of rapidly obtaining metabolomic phenotype data in both prokaryotes and eukaryotes. Given our generally poor understanding of Campylobacter metabolism, the hig...

    Robert M. Howlett, Matthew P. Davey, David J. Kelly in Campylobacter jejuni (2017)

  7. Article

    Open Access

    Metabolomic analysis of the food-borne pathogen Campylobacter jejuni: application of direct injection mass spectrometry for mutant characterisation

    Campylobacter jejuni is the most frequent cause of human food-borne bacterial gastroenteritis but its physiology and biochemistry are poorly understood. Only a few amino-acids can be cat...

    Robert M. Howlett, Matthew P. Davey, W. Paul Quick, David J. Kelly in Metabolomics (2014)

  8. No Access

    Article

    Evaluation of attractant flavours for use in oral vaccine baits for badgers (Meles meles)

    European badgers (Meles meles) are a wildlife reservoir for Mycobacterium bovis infection (tuberculosis) in Ireland and the UK and are implicated in the transmission of infection to livestock. Vaccination of badg...

    David J. Kelly, Leigh A. L. Corner, Eamonn Gormley in European Journal of Wildlife Research (2011)

  9. No Access

    Article

    Changes in trophic linkages to shortfin eels (Anguilla australis) since the collapse of submerged macrophytes in Lake Ellesmere, New Zealand

    Lake Ellesmere (Te Waihora) is a nationally important coastal brackish lake in New Zealand, however degradation in water quality and loss of submerged macrophytes over past decades have raised concerns in rega...

    David J. Kelly, Don J. Jellyman in Hydrobiologia (2007)

  10. No Access

    Chapter

    Chapter 3: Respiratory Electron Transport in Helicobacter and campylobacter

    The microaerophilic, human gastro-intestinal pathogens, Campylobacter jejuni and Helicobacter pylori are closely related phylogentically, yet distinct in some major aspects of their physiology, especially with re...

    Jonathan D. Myers, David J. Kelly in Respiration in Archaea and Bacteria (2004)

  11. No Access

    Chapter

    High-Affinity C4-Dicarboxylate Uptake in Rhodobacter Capsulatus Is Mediated By A ‘Trap’ Transporter, A New Type of Periplasmic Secondary Transport System Widespread in Bacteria

    Anoxygenic photosynthetic bacteria in the purple non-sulphur group have long been known to grow rapidly and with high yields on certain citric-acid cycle intermediates and their precursors, particularly pyruva...

    David J. Kelly, Neil R. Wyborn, Mark Gibson in The Phototrophic Prokaryotes (1999)

  12. No Access

    Protocol

    Use of NMR to Study H. pylori Metabolism

    Until recently, the culture of Helicobacter pylori in vitro has only been achievable with complex undefined media supplemented with blood products, such as Brain-heart infusion (BHI) medium, blood agar, chocolate...

    Peter A. Chalk, Andrew D. Roberts, Alistair A. Davison in Helicobacter pylori Protocols (1997)

  13. No Access

    Chapter

    Flagellate Motility, Behavioral Responses and Active Transport in Purple Non-Sulfur Bacteria

    Judith P. Armitage, David J. Kelly in Anoxygenic Photosynthetic Bacteria (1995)

  14. No Access

    Article

    An enzyme and13C-NMR study of carbon metabolism in heliobacteria

    Heliobacteria are a group of anoxygenic phototrophs that can grow photoheterotrophically in defined minimal media on only a limited range of organic substrates as carbon sources. In this study the mechanisms w...

    Mark W. Pickett, Michael P. Williamson, David J. Kelly in Photosynthesis Research (1994)

  15. No Access

    Article

    Sequence analysis and interposon mutagenesis of a sensor-kinase (DctS) and response-regulator (DctR) controlling synthesis of the high-affinity C4-dicarboxylate transport system in Rhodobacter capsulatus

    A two-component sensor-regulator system has been identified in the purple photosynthetic bacterium Rhodobacter capsulatus, which controls the expression of high-affinity C4-dicarboxylate transport activity in the...

    Mark J. Hamblin, Jonathan G. Shaw, David J. Kelly in Molecular and General Genetics MGG (1993)

  16. No Access

    Article

    Anaerobic degradation of trans-cinnamate and ω-phenylalkane carboxylic acids by the photosynthetic bacterium Rhodopseudomonas palustris: evidence for a β-oxidation mechanism

    The mechanism responsible for the initial steps in the anaerobic degradation of trans-cinnamate and ω-phenylalkane carboxylates by the purple non-sulphur photosynthetic bacterium Rhodopseudomonas palustris was in...

    Douglas J. E. Elder, Philip Morgan, David J. Kelly in Archives of Microbiology (1992)

  17. No Access

    Article

    Binding protein dependent transport of C4-dicarboxylates in Rhodobacter capsulatus

    The characteristics of malate transport into aerobically grown cells of the purple photosynthetic bacterium Rhodobacter capsulatus were determined. A single transport system was distinguished kinetically which di...

    Jonathan G. Shaw, David J. Kelly in Archives of Microbiology (1991)

  18. No Access

    Chapter

    Physiology and Genetics of C4-Dicarboxylate Transport in Rhodobacter capsulatus

    Of those carbon sources traditionally used in studies on purple non-sulphur bacteria, the C4-dicarboxylic acids malate and succinate have long been known to be particularly effective in promoting fast growth r...

    David J. Kelly, Mark J. Hamblin in Molecular Biology of Membrane-Bound Comple… (1990)

  19. Article

    The role of auxiliary oxidants in maintaining redox balance during phototrophic growth of Rhodobacter capsulatuspropionate or butyrate

    David J. Richardson, Glenn F. King, David J. Kelly in Archives of Microbiology (1988)

  20. No Access

    Article

    The role of auxiliary oxidants in maintaining redox balance during phototrophic growth of Rhodobacter capsulatus on propionate or butyrate

    Phototrophic growth of Rhodobacter capsulatus (formerly Rhodopseudomonas capsulata) under anaerobic conditions with either butyrate or propionate as carbonsource was dependent on the presence of either CO2 or an ...

    David J. Richardson, Glenn F. King, David J. Kelly in Archives of Microbiology (1988)