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  1. Article

    Open Access

    Structure-preserving formulations for data-driven analysis of coupled multi-physics systems

    We develop a novel methodology for data-driven simulation of coupled multi-physics systems. The result of the method is a learned numerical integrator of the coupled system dynamics. In order to preserve the f...

    Alba Muixí, David González, Francisco Chinesta, Elías Cueto in Computational Mechanics (2024)

  2. No Access

    Article

    Computational Sensing, Understanding, and Reasoning: An Artificial Intelligence Approach to Physics-Informed World Modeling

    This work offers a discussion on how computational mechanics and physics-informed machine learning can be integrated into the process of sensing, understanding, and reasoning of physical phenomena. A foundatio...

    Beatriz Moya, Alberto Badías, David González in Archives of Computational Methods in Engin… (2024)

  3. No Access

    Chapter and Conference Paper

    Hybrid Maximal Filter Spaces

    We introduce a new way of encoding general topology in second order arithmetic that we call hybrid maximal filter (hybrid MF) spaces. This notion is a modification of the notion of a proper MF space introduced...

    David Gonzalez in Twenty Years of Theoretical and Practical Synergies (2024)

  4. Article

    Open Access

    A thermodynamics-informed active learning approach to perception and reasoning about fluids

    Learning and reasoning about physical phenomena is still a challenge in robotics development, and computational sciences play a capital role in the search for accurate methods able to provide explanations for ...

    Beatriz Moya, Alberto Badías, David González, Francisco Chinesta in Computational Mechanics (2023)

  5. Article

    Open Access

    Older adults, clinicians, and researchers’ preferences for measuring adherence to resistance and balance exercises

    Resistance and balance training are important exercise interventions for older populations living with chronic diseases. Accurately measuring if an individual is adhering to exercises as prescribed is importan...

    Caitlin McArthur, Gabriella Duhaime, David Gonzalez, Nanna Notthoff in BMC Geriatrics (2023)

  6. No Access

    Article

    Management of high-risk and post-operative non-metastatic prostate cancer in Catalonia: an expert Delphi consensus

    To reach a consensus on recommendations for the management of high-risk and post-operative non-metastatic prostate cancer by a group of Radiation Oncologists in Catalonia dedicated to prostate cancer.

    Marta Bonet, David González, José-Enrique Baquedano in Clinical and Translational Oncology (2023)

  7. No Access

    Protocol

    Detection of Endophytes by Cultivation Method

    Detection of endophytes can be performed through several techniques, among them, the so-called “Fragment Culture technique” is one of the oldest and more used ones. Until the advent of molecular biology techni...

    Paula Rodríguez, David Gonzalez in Endophytic Microbes: Isolation, Identifica… (2023)

  8. No Access

    Chapter and Conference Paper

    The Smart Accreditation (SAcre): An IoT Context-Aware Computing Solution for Identification

    Identification is an important process when we are in collectivity. Thus, we have to adapt technologies to facilitate many functionalities that can be addressed only by means of a simple identification infrast...

    José Bravo, Iván González, Cosmin Dobrescu in Proceedings of the International Conferenc… (2023)

  9. No Access

    Protocol

    Screening of Endophytes for Biocatalytic Tools

    Endophytic communities thrive in environments that are rich in biologically active compounds. To survive, endophytes have adapted to produce secondary metabolites mimicking their host plant and synthesize the ...

    David Gonzalez, Emiliana Botto in Endophytic Microbes: Isolation, Identifica… (2023)

  10. Article

    Open Access

    Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus

    Crimean-Congo Hemorrhagic Fever Virus (CCHFV) causes a life-threatening disease with up to a 40% mortality rate. With no approved medical countermeasures, CCHFV is considered a public health priority agent. Th...

    Ian A. Durie, Zahra R. Tehrani, Elif Karaaslan, Teresa E. Sorvillo in Nature Communications (2022)

  11. Article

    Open Access

    Development of LTCC-packaged optocouplers as optical galvanic isolation for high-temperature applications

    This paper reports high-temperature optocouplers for signal galvanic isolation. Low temperature co-fired ceramic (LTCC) technology was used in the design and fabrication of the high-temperature optocoupler pac...

    Pengyu Lai, David Gonzalez, Syam Madhusoodhanan, Abbas Sabbar in Scientific Reports (2022)

  12. Article

    Open Access

    High-temperature analysis of optical coupling using AlGaAs/GaAs LEDs for high-density integrated power modules

    A low-temperature co-fired ceramic (LTCC)-based optocoupler design is demonstrated as a possible solution for optical isolation in high-density integrated power modules. The design and fabrication of LTCC base...

    Syam Madhusoodhanan, Abbas Sabbar, Huong Tran, Pengyu Lai in Scientific Reports (2022)

  13. Protocol

    Immunoglobulin/T Cell Receptor Capture Strategy for Comprehensive Immunogenetics

    In the era of genomic medicine, targeted next generation sequencing strategies (NGS) are becoming increasingly adopted by clinical molecular diagnostic laboratories to identify genetic diagnostic and prognosti...

    James Peter Stewart, Jana Gazdova, Shambhavi Srivastava, Julia Revolta in Immunogenetics (2022)

  14. Chapter

    The DeepHealth Toolkit: A Key European Free and Open-Source Software for Deep Learning and Computer Vision Ready to Exploit Heterogeneous HPC and Cloud Architectures

    At the present time, we are immersed in the convergence between Big Data, High-Performance Computing and Artificial Intelligence. Technological progress in these three areas has accelerated in recent years, fo...

    Marco Aldinucci, David Atienza in Technologies and Applications for Big Data… (2022)

  15. Article

    Open Access

    Secondary metabolites, antibacterial and antioxidant properties of the leaf extracts of Acacia rigidula benth. and Acacia berlandieri benth.

    The use of plants as sources for novel antimicrobial as well as antioxidant agents offers advantages. Plants are readily accessible and inexpensive, extracts or compounds from plant sources often demonstrate h...

    Peter Cavazos, David Gonzalez, Jocelyn Lanorio, Ruby Ynalvez in SN Applied Sciences (2021)

  16. Article

    Open Access

    Inhibition of casein kinase 1 δ/ε improves cognitive performance in adult C57BL/6J mice

    Time-of-day effects have been noted in a wide variety of cognitive behavioral tests, and perturbation of the circadian system, either at the level of the master clock in the SCN or downstream, impairs hippocam...

    Heather Mahoney, Emily Peterson, Hannah Justin, David Gonzalez in Scientific Reports (2021)

  17. Article

    Open Access

    Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms

    Gulf War illness (GWI) afflicts military personnel who served during the Persian Gulf War and is notable for cognitive deficits, depression, muscle pain, weakness, intolerance to exercise, and fatigue. Suspect...

    Israel Ramirez-Sanchez, Viridiana Navarrete-Yañez in Scientific Reports (2020)

  18. No Access

    Article

    Prevalence and characterization of β-lactamase-producing Enterobacteriaceae in healthy human carriers

    Presence of extended-spectrum β-lactamase (ESBL-E), AmpC-producing and carbapenemase-producing (CPE) Enterobacteriaceae has been observed not only in the clinical environment, but also in the out-of-hospital envi...

    David González, Eibhlin Gallagher, Teresa Zúñiga, José Leiva in International Microbiology (2020)

  19. Article

    Open Access

    Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study

    Amplicon-based next-generation sequencing (NGS) of immunoglobulin (IG) and T-cell receptor (TR) gene rearrangements for clonality assessment, marker identification and quantification of minimal residual diseas...

    Monika Brüggemann, Michaela Kotrová, Henrik Knecht, Jack Bartram in Leukemia (2019)

  20. Article

    Open Access

    Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS

    Assessment of clonality, marker identification and measurement of minimal residual disease (MRD) of immunoglobulin (IG) and T cell receptor (TR) gene rearrangements in lymphoid neoplasms using next-generation ...

    Henrik Knecht, Tomas Reigl, Michaela Kotrová, Franziska Appelt, Peter Stewart in Leukemia (2019)

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