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Article
Wound management materials and technologies from bench to bedside and beyond
Chronic wounds represent a major global health problem, causing staggering economic and social burdens. The pursuit of effective wound healing strategies demands a multidisciplinary approach, and advances in m...
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Article
Comparison of bacterial species and clinical outcomes in patients with diabetic hand infection in tropical and nontropical regions
Hand infection is a rare complication in patients with diabetes. Its clinical outcomes depend on the severity of hand infection caused by bacteria, but the difference in bacterial species in the regional dispa...
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Article
Open AccessReal-World Racial Variation in Treatment and Outcomes Among Patients with Peripheral Artery Disease
Prior studies have found considerable disparities in prevalence and outcomes for patients with peripheral arterial disease (PAD). This study compared rates of diagnostic testing, treatment patterns, and outcom...
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Article
Open AccessMortality prediction in patients with hyperglycaemic crisis using explainable machine learning: a prospective, multicentre study based on tertiary hospitals
Experiencing a hyperglycaemic crisis is associated with a short- and long-term increased risk of mortality. We aimed to develop an explainable machine learning model for predicting 3-year mortality and providi...
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Chapter
Seeing a Patient with a Wound
Lower extremity wound management in patients with peripheral vascular disease can be daunting. The initial assessment consists of a physical exam of the wound, vascular status stratification, and risk factor m...
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Article
Open AccessA qualitative study of barriers to care-seeking for diabetic foot ulceration across multiple levels of the healthcare system
The mechanisms for the observed disparities in diabetes-related amputation are poorly understood and could be related to access for diabetic foot ulceration (DFU) care. This qualitative study aimed to understa...
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Article
Current Management of Peripheral Artery Disease: Focus on Pharmacotherapy
Peripheral artery disease (PAD) is the occlusion or narrowing of the arteries supplying the lower extremities. Peripheral artery disease has been estimated to affect approximately 240 million people worldwide,...
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Article
Open AccessCorrection to: MRI nomenclature for musculoskeletal infection
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Chapter and Conference Paper
Diabetic Foot Ulcer Grand Challenge 2021: Evaluation and Summary
Diabetic foot ulcer classification systems use the presence of wound infection (bacteria present within the wound) and ischaemia (restricted blood supply) as vital clinical indicators for treatment and predict...
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Article
Open AccessMRI nomenclature for musculoskeletal infection
The Society of Skeletal Radiology (SSR) Practice Guidelines and Technical Standards Committee identified musculoskeletal infection as a White Paper topic, and selected a Committee, tasked with develo** a con...
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Chapter
Biologic Tools for Genetic Engineering Chronic Wounds
Wound healing approaches traditionally have targeted controlling environmental aspects of the wound and neighboring tissues. Genetic engineering researchers have sought to take a different approach. Instead of...
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Chapter
The Promise and Hurdles of Telemedicine in Diabetes Foot Care Delivery
Almost half of people with diabetes have peripheral nerve dysfunction (neuropathy; PN) or poor blood supply to the lower limb caused by diabetes or peripheral artery disease (PAD). They are at a high risk of d...
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Article
Open AccessThe dynamic wound microbiome
Diabetic foot ulcers (DFUs) account for the majority of all limb amputations and hospitalizations due to diabetes complications. With 30 million cases of diabetes in the USA and 500,000 new diagnoses each year...
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Article
Open AccessFive year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer
In 2007, we reported a summary of data comparing diabetic foot complications to cancer. The purpose of this brief report was to refresh this with the best available data as they currently exist. Since that tim...
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Article
Open AccessUlcer metastasis? Anatomical locations of recurrence for patients in diabetic foot remission
The “cancer analogy” is powerful for communicating risk to and organizing care for patients with diabetic foot syndrome. One potentially underappreciated similarity between cancer and foot ulcers is that both ...
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Chapter
Management of Diabetic Foot Ulcers: Offloading and Debridement
Diabetic foot ulcer and its complications are common, costly, and challenging. Diabetic peripheral neuropathy, foot deformity, and trauma are three contributors to diabetic foot ulcerations. Evaluation of diab...
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Chapter
Pathophysiology and Principles of Management of the Diabetic Foot
Diabetic foot complications are the main cause of non-traumatic lower limb amputation internationally. Most amputations in diabetes are preceded by foot ulceration. Therefore, a thorough understanding of the c...
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Article
A histologically hostile environment made more hospitable?
Up to one-third of patients with diabetes mellitus will develop a diabetic foot ulcer in their lifetime. While this number appears to be rising, breakthrough therapies for this common, complex and costly condi...
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Article
Open AccessEfficacy and long-term longitudinal follow-up of bone marrow mesenchymal cell transplantation therapy in a diabetic patient with recurrent lower limb bullosis diabeticorum
Bullosis diabeticorum is a rare presentation of cutaneous manifestation most commonly affecting the lower limbs in patients with diabetes. The appearance, often as insidious as its resolution, is characterized...
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Article
Open AccessDiabetic Foot Australia guideline on footwear for people with diabetes
The aim of this paper was to create an updated Australian guideline on footwear for people with diabetes.