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  1. No Access

    Article

    Fast Compatibility Testing for Rooted Phylogenetic Trees

    We present a new graph-based approach to the following basic problem in phylogenetic tree construction. Let $$\mathcal {P}= \{T_1, \ld...

    Yun Deng, David Fernández-Baca in Algorithmica (2018)

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    Chapter and Conference Paper

    Fast Compatibility Testing for Phylogenies with Nested Taxa

    Semi-labeled trees are phylogenies whose internal nodes may be labeled by higher-order taxa. Thus, a leaf labeled Mus musculus could nest within a subtree whose root node is labeled Rodentia, which itself could n...

    Yun Deng, David Fernández-Baca in Algorithms in Bioinformatics (2016)

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    Chapter and Conference Paper

    Constructing and Employing Tree Alignment Graphs for Phylogenetic Synthesis

    Tree alignment graphs (TAGs) provide an intuitive data structure for storing phylogenetic trees that exhibits the relationships of the individual input trees and can potentially account for nested taxonomic re...

    Ruchi Chaudhary, David Fernández-Baca in Algorithms for Computational Biology (2015)

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    Article

    EvoMiner: frequent subtree mining in phylogenetic databases

    The problem of mining collections of trees to identify common patterns, called frequent subtrees (FSTs), arises often when trying to interpret the results of phylogenetic analysis. FST mining generalizes the w...

    Akshay Deepak, David Fernández-Baca in Knowledge and Information Systems (2014)

  5. Article

    Editorial

    David Fernández-Baca in Algorithmica (2014)

  6. No Access

    Chapter and Conference Paper

    Characterizing Compatibility and Agreement of Unrooted Trees via Cuts in Graphs

    Deciding whether there is a single tree —a supertree— that summarizes the evolutionary information in a collection of unrooted trees is a fundamental problem in phylogenetics. We consider two versions of this ...

    Sudheer Vakati, David Fernández-Baca in Algorithms in Bioinformatics (2013)

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    Book and Conference Proceedings

    LATIN 2012: Theoretical Informatics

    10th Latin American Symposium, Arequipa, Peru, April 16-20, 2012. Proceedings

    David Fernández-Baca in Lecture Notes in Computer Science (2012)

  8. No Access

    Chapter and Conference Paper

    Improved Lower Bounds on the Compatibility of Quartets, Triplets, and Multi-state Characters

    We study a long standing conjecture on the necessary and sufficient conditions for the compatibility of multi-state characters: There exists a function f(r) such that, for any set C of r-state characters, C is co...

    Brad Shutters, Sudheer Vakati, David Fernández-Baca in Algorithms in Bioinformatics (2012)

  9. No Access

    Chapter and Conference Paper

    Fixed-Parameter Algorithms for Finding Agreement Supertrees

    We study the agreement supertree approach for combining rooted phylogenetic trees when the input trees do not fully agree on the relative positions of the taxa. Two approaches to dealing with such conflicting ...

    David Fernández-Baca, Sylvain Guillemot, Brad Shutters in Combinatorial Pattern Matching (2012)

  10. No Access

    Chapter and Conference Paper

    Identifying Rogue Taxa through Reduced Consensus: NP-Hardness and Exact Algorithms

    A rogue taxon in a collection of phylogenetic trees is one whose position varies drastically from tree to tree. The presence of such taxa can greatly reduce the resolution of the consensus tree (e.g., the majo...

    Akshay Deepak, Jianrong Dong in Bioinformatics Research and Applications (2012)

  11. No Access

    Chapter and Conference Paper

    Extracting Conflict-Free Information from Multi-labeled Trees

    A multi-labeled tree, or MUL-tree, is a phylogenetic tree where two or more leaves share a label, e.g., a species name. A MUL-tree can imply multiple conflicting phylogenetic relationships for the same set of ...

    Akshay Deepak, David Fernández-Baca, Michelle M. McMahon in Algorithms in Bioinformatics (2012)

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    Chapter and Conference Paper

    Fast Local Search for Unrooted Robinson-Foulds Supertrees

    A Robinson-Foulds (RF) supertree for a collection of input trees is a comprehensive species phylogeny that is at minimum total RF distance to the input trees. Thus, an RF supertree is consistent with the maxim...

    Ruchi Chaudhary, J. Gordon Burleigh in Bioinformatics Research and Applications (2011)

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    Chapter and Conference Paper

    Constructing Large Conservative Supertrees

    Generalizations of the strict and loose consensus methods to the supertree setting, recently introduced by McMorris and Wilkinson, are studied. The supertrees these methods produce are conservative in the sens...

    Jianrong Dong, David Fernández-Baca in Algorithms in Bioinformatics (2011)

  14. No Access

    Chapter and Conference Paper

    Comparing and Aggregating Partially Resolved Trees

    We define, analyze, and give efficient algorithms for two kinds of distance measures for rooted and unrooted phylogenies. For rooted trees, our measures are based on the topologies the input trees induce on tripl...

    Mukul S. Bansal, Jianrong Dong, David Fernández-Baca in LATIN 2008: Theoretical Informatics (2008)

  15. No Access

    Chapter and Conference Paper

    Parametric Analysis for Ungapped Markov Models of Evolution

    We present efficient sensitivity-analysis algorithms for two problems involving Markov models of sequence evolution: ancestral reconstruction in evolutionary trees and local ungapped alignment under log-odds s...

    David Fernández-Baca, Balaji Venkatachalam in Combinatorial Pattern Matching (2005)

  16. No Access

    Chapter and Conference Paper

    Supertrees by Flip**

    The input to a supertree problem is a collection of phyloge-netic trees that intersect pairwise in their leaf sets; the goal is to construct a single tree that retains as much as possible of the information in...

    D. Chen, O. Eulenstein, David Fernández-Baca, M. Sanderson in Computing and Combinatorics (2002)

  17. No Access

    Chapter and Conference Paper

    Inverse Parametric Sequence Alignment

    We consider the inverse parametric sequence alignment problem, where a sequence alignment is given and the task is to determine parameter values such that the given alignment is optimal at that parameter setti...

    Fangting Sun, David Fernández-Baca, Wei Yu in Computing and Combinatorics (2002)

  18. No Access

    Chapter

    The Perfect Phylogeny Problem

    A phylogeny is a tree representation of the evolutionary history of a set of taxa (organisms, biological sequences, populations, or languages). Thus, phylogeny construction is among the basic computational proble...

    David Fernández-Baca in Steiner Trees in Industry (2001)

  19. No Access

    Chapter and Conference Paper

    Multi-parameter Minimum Spanning Trees

    A framework for solving certain multidimensional parametric search problems in randomized linear time is presented, along with its application to optimization on matroids, including parametric minimum spanning...

    David Fernández-Baca in LATIN 2000: Theoretical Informatics (2000)

  20. No Access

    Chapter and Conference Paper

    Parametric Multiple Sequence Alignment and Phylogeny Construction

    Bounds are given on the size of the parameter-space decomposition induced by multiple sequence alignment problems where phylogenetic information may be given or inferred. It is shown that many of the usual for...

    David Fernández-Baca, Timo Seppäläinen, Giora Slutzki in Combinatorial Pattern Matching (2000)

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