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  1. No Access

    Article

    History of endoscopic treatment of vesicoureteral reflux

    Since its first clinical application in 1984, the endoscopic subureteral injection of bulking agents has become an alternative to long-term antibiotic prophylaxis and open surgical intervention in the treatmen...

    Balazs Kutasy, David Coyle in Pediatric Surgery International (2023)

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    Chapter

    Posterior Urethral Valves

    Posterior urethral valves (PUV) is the most common congenital cause of lower urinary tract obstruction (LUTO), accounting for over half (57%) of all reported cases. The large majority of patients with PUV are ...

    Salvatore Cascio, David Coyle, Simona Nappo, Paolo Caione in Pediatric Surgery (2023)

  3. Article

    Open Access

    Examining the effect of Libet clock stimulus parameters on temporal binding

    Temporal binding refers to the subjective temporal compression between actions and their outcomes. It is widely used as an implicit measure of sense of agency, that is, the experience of controlling our action...

    Bianca E. Ivanof, Devin B. Terhune, David Coyle, Marta Gottero in Psychological Research (2022)

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    Article

    Addressing the complexity of personalized, context-aware and health-aware food recommendations: an ensemble topic modelling based approach

    Food Recommender Systems (FRS) have the potential to support informed and satisfying food choices. However, to realize their full potential, FRS must engage with the complexity of the choices people make aroun...

    Mansura A. Khan, Barry Smyth, David Coyle in Journal of Intelligent Information Systems (2021)

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    Reference Work Entry In depth

    Hemangiomas and Other Vascular Anomalies

    A wide spectrum of vascular anomalies exists and the International Society for the Study of Vascular Anomalies (ISSVA) have classified all known lesions as either vascular tumors (benign, borderline, malignant...

    David Coyle, Alan E. Mortell in Pediatric Surgery (2021)

  6. No Access

    Reference Work Entry In depth

    Appendicitis

    Appendicitis is a surgical emergency, characterized classically by right lower quadrant pain, vomiting, and fever, due to an inflamed vermiform appendix. The lifetime risk of develo** acute appendicitis is a...

    Alan E. Mortell, David Coyle in Pediatric Surgery (2021)

  7. No Access

    Reference Work Entry In depth

    Teratomas (All Locations)

    Teratomas are the most common form of germ cell tumors in children. Sacrococcygeal teratoma (SCT) is the most common teratoma presenting at birth. Fetuses with “high risk” SCT have a mortality rate of 40%–50%....

    Thambipillai Sri Paran, David Coyle in Pediatric Surgery (2021)

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    Reference Work Entry In depth

    Gastric Volvulus

    Gastric volvulus (GV) is a rare surgical emergency, defined by the abnormal rotation of a part of the stomach around another part, leading to obstruction and, in some cases, tissue ischemia and necrosis. Anato...

    Alan E. Mortell, David Coyle in Pediatric Surgery (2020)

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    Living Reference Work Entry In depth

    Hemangiomas and Other Vascular Anomalies

    A wide spectrum of vascular anomalies exists and the International Society for the Study of Vascular Anomalies (ISSVA) have classified all known lesions as either vascular tumors (benign, borderline, malignant...

    David Coyle, Alan E. Mortell in Pediatric Surgery

  10. No Access

    Living Reference Work Entry In depth

    Teratomas (All Locations)

    Teratomas are the most common form of germ cell tumors in children. Sacrococcygeal teratoma (SCT) is the most common teratoma presenting at birth. Fetuses with “high risk” SCT have a mortality rate of 40%–50%....

    Thambipillai Sri Paran, David Coyle in Pediatric Surgery

  11. No Access

    Living Reference Work Entry In depth

    Appendicitis (General Pediatric Surgery of Abdomen)

    Appendicitis is a surgical emergency, characterized classically by right lower quadrant pain, vomiting, and fever, due to an inflamed vermiform appendix. The lifetime risk of develo** acute appendicitis is a...

    Alan E. Mortell, David Coyle in Pediatric Surgery

  12. No Access

    Article

    Altered expression of caveolin-1 in the colon of patients with Hirschsprung’s disease

    The pathogenesis of Hirschsprung’s disease-associated enterocolitis (HAEC) is unclear. Caveolin-1 (Cav-1) regulates the functions of different nitric oxide synthase (NOS) isoforms, which play critical roles in...

    Hiroki Nakamura, Anne Marie O’Donnell in Pediatric Surgery International (2019)

  13. No Access

    Chapter

    Laparoscopic Leveling Colostomy for Colonic Aganglionosis

    This chapter describes the surgical procedure for laparoscopic leveling colostomy for colonic aganglionosis as performed by the following approaches: open and laparoscopic. The text includes an introduction th...

    David Coyle, Karen A. Diefenbach in Operative Dictations in Pediatric Surgery (2019)

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    Chapter

    Aspiration/Drainage of Breast Abscess

    This chapter describes the surgical procedure for aspiration/drainage of breast abscess as performed by the following approaches: In most cases, a percutaneous ultrasound-guided drainage, when used in conjunct...

    David Coyle in Operative Dictations in Pediatric Surgery (2019)

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    Chapter

    Association Between Hirschsprung’s Disease and Multiple Endocrine Neoplasia

    A “loss-of-function” mutation of the RET proto-oncogene is the most common genetic aberration implicated in the pathogenesis of Hirschsprung’s disease (HSCR). Some individuals with HSCR harbour RET mutations, whi...

    David Coyle, Prem Puri in Hirschsprung's Disease and Allied Disorders (2019)

  16. No Access

    Article

    Altered expression of inflammasomes in Hirschsprung’s disease

    The pathogenesis of Hirschsprung’s disease-associated enterocolitis (HAEC) is poorly understood. Inflammasomes are a large family of multiprotein complexes that act to mediate host immune responses to microbia...

    Hiroki Nakamura, Anne Marie O’Donnell in Pediatric Surgery International (2019)

  17. No Access

    Chapter

    Hirschsprung’s Disease

    Hirschsprung’s disease (HD) is characterised by an absence of ganglion cells in the distal bowel extending proximally for varying distances. The absence of ganglion cells has been attributed to failure of migr...

    Prem Puri, David Coyle in Pediatric Surgery (2019)

  18. No Access

    Chapter

    Laparoscopic Colonic Map**

    This chapter describes colonic map** for Hirschsprung’s disease as performed by the following approaches: open (first) and laparoscopic. The text includes an introduction that outlines the indications, risks...

    David Coyle, Karen A. Diefenbach in Operative Dictations in Pediatric Surgery (2019)

  19. No Access

    Chapter

    Morphological Basis of Persistent Bowel Problems Following a Properly Performed Pull-Through Operation for Hirschsprung’s Disease

    Despite having a technically satisfactory pull-through operation for Hirschsprung’s disease (HSCR) (complete resection of all aganglionic or hypoganglionic colon with hypertrophic nerve trunks while avoiding i...

    David Coyle, Prem Puri in Hirschsprung's Disease and Allied Disorders (2019)

  20. No Access

    Article

    Altered goblet cell function in Hirschsprung’s disease

    Hirschsprung’s disease-associated enterocolitis (HAEC) is the most serious complication of Hirschsprung’s disease (HSCR). HAEC occurs in 17–50% of patients with HSCR and may occur before or after a properly pe...

    Hiroki Nakamura, Christian Tomuschat, David Coyle in Pediatric Surgery International (2018)

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