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Article
Open AccessDynamics of collagen oxidation and cross linking in regenerating and irreversibly infarcted myocardium
In mammalian hearts myocardial infarction produces a permanent collagen-rich scar. Conversely, in zebrafish a collagen-rich scar forms but is completely resorbed as the myocardium regenerates. The formation of...
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Article
Open AccessTranscriptome analysis of pancreatic cells across distant species highlights novel important regulator genes
Defining the transcriptome and the genetic pathways of pancreatic cells is of great interest for elucidating the molecular attributes of pancreas disorders such as diabetes and cancer. As the function of the d...
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Article
Open AccessProgenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration
In contrast to mammals, the zebrafish has the remarkable capacity to regenerate its pancreatic beta cells very efficiently. Understanding the mechanisms of regeneration in the zebrafish and the differences wit...