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Open AccessDuration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)
Key questions in COVID-19 are the duration and determinants of infectious virus shedding. Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 patients (17.8%) hospital...
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Article
Transmission of HIV in sexual networks in sub-Saharan Africa and Europe
We are reviewing the literature regarding sexual networks and HIV transmission in sub-Saharan Africa and Europe. On Likoma Island in Malawi, a sexual network was reconstructed using a sociometric survey in whi...
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Article
Inferring epidemiological parameters from phylogenetic information for the HIV-1 epidemic among MSM
The HIV-1 epidemic in Europe is primarily sustained by a dynamic topology of sexual interactions among MSM who have individual immune systems and behavior. This epidemiological process shapes the phylogeny of ...
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Article
Open AccessEvolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: from treatment to prevention
The HIV epidemic continues unabated, with no highly effective vaccine and no cure. Each new infection has significant economic, social and human costs and prevention efforts are now as great a priority as glob...
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Article
Open AccessLimited cross-border infections in patients newly diagnosed with HIV in Europe
International travel plays a role in the spread of HIV-1 across Europe. It is, however, not known whether international travel is more important for spread of the epidemic as compared to endogenous infections ...
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Article
Decrease of antiparkinsonian drugs before start of an antipsychotic in patients on levodopa treatment?
Introduction: Antiparkinsonian drugs can induce behavioural disturbances, which should be treated by first reducing antiparkinsonian drugs and/or starting a benzodiazepine. If this approach fails, then antipsy...