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Article
Open AccessOptogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin
The common final pathway to blindness in many forms of retinal degeneration is the death of the light-sensitive primary retinal neurons. However, the normally light-insensitive second- and third-order neurons ...
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Article
Open AccessThe temporal structure of the inner retina at a single glance
The retina decomposes visual stimuli into parallel channels that encode different features of the visual environment. Central to this computation is the synaptic processing in a dense layer of neuropil, the so...
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Article
Open AccessCannabinoid-induced increase of quantal size and enhanced neuromuscular transmission
Cannabinoids exert dynamic control over many physiological processes including memory formation, cognition and pain perception. In the central nervous system endocannabinoids mediate negative feedback of quant...
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Article
Open AccessThe impact of inhibitory mechanisms in the inner retina on spatial tuning of RGCs
Spatial tuning properties of retinal ganglion cells (RGCs) are sharpened by lateral inhibition originating at both the outer and inner plexiform layers. Lateral inhibition in the retina contributes to local co...
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Article
P/Q-type calcium channels activate neighboring calcium-dependent potassium channels in mouse motor nerve terminals
The identity of the voltage-dependent calcium channels (VDCC), which trigger the Ca2+-gated K+ currents (I K(Ca)) in mammalian motor nerve terminals, was investigated by means of perineurial recordings. The effe...
