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Article
Open AccessStratifin (SFN) Regulates Cervical Cancer Cell Proliferation, Apoptosis, and Cytoskeletal Remodeling and Metastasis Progression Through LIMK2/Cofilin Signaling
The aberrant expression of Stratifin (SFN) is intricately associated with the initiation and progression of numerous tumors. This study aims to investigate whether SFN regulates the metastasis of cervical canc...
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Article
Open AccessEvaluation of a population-based breast cancer screening in North China
Despite mammography-based screening for breast cancer has been conducted in many countries, there are still little data on participation and diagnostic yield in population-based breast cancer screening in China.
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Article
Effect of high-level PM2.5 on survival in lung cancer: a multicenter cohort study from Hebei Province, China
Globally, air pollution is the fourth leading risk factor for death, while lung cancer (LC) is the leading cause of cancer-related death. The aim of this study was to explore the prognostic factors of LC and t...
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Article
Open AccessLung cancer risk and exposure to air pollution: a multicenter North China case–control study involving 14604 subjects
For North Chinese lung cancer patients, there is limited study on the distribution of air pollution and smoking related features based on analyses of large-scale, high-quality population datasets. The aim of t...
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Article
Open AccessCost-effectiveness evaluation of risk-based breast cancer screening in Urban Hebei Province
To evaluate the implementations of Cancer Screening Program in Urban Hebei and to model the cost-effectiveness of a risk-based breast Cancer Screening Program. Women aged 40–74 years were invited to participat...
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Article
MicroRNA-29b regulates the radiosensitivity of esophageal squamous cell carcinoma by regulating the BTG2-mediated cell cycle
Many patients with esophageal squamous cell carcinoma (ESCC) are inoperable due to old age or advanced stage; thus, radio- and chemotherapy are considered the standard treatments for these patients. However, d...
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Article
Open AccessEpidemiology and prognosis in young lung cancer patients aged under 45 years old in northern China
To explore the epidemiological characteristics and prognosis of lung cancer in patients aged under 45 years old in northern China. The population-based database about lung cancer cases aged under 45y selected ...
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Article
Open AccessTrends and Patterns of Cancer Mortality in North China (Hebei Province), 1973–2013
Little was known about the cancer burden for the last 40 years in middle-income province in China. This study aimed to assess the overall, cause-specific mortality cancer trend and disability-adjusted life yea...
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Article
Generation and characterization of a novel human IgG1 antibody against vascular endothelial growth factor receptor 2
VEGF and its receptors, especially VEGFR2 (KDR), are known to play a critical role in angiogenesis under both physiological and pathological conditions, including cancer and angiogenic retinopathies. This stud...
