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  1. Article

    Open Access

    PitSurgRT: real-time localization of critical anatomical structures in endoscopic pituitary surgery

    Endoscopic pituitary surgery entails navigating through the nasal cavity and sphenoid sinus to access the sella using an endoscope. This procedure is intricate due to the proximity of crucial anatomical struct...

    Zhehua Mao, Adrito Das, Mobarakol Islam in International Journal of Computer Assisted… (2024)

  2. Article

    Open Access

    Early evaluation of a natural language processing tool to improve access to educational resources for surgical patients

    Accessible patient information sources are vital in educating patients about the benefits and risks of spinal surgery, which is crucial for obtaining informed consent. We aim to assess the effectiveness of a n...

    James Booker, Jack Penn, Kawsar Noor, Richard J. B. Dobson in European Spine Journal (2024)

  3. Article

    Author Correction: The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring

    Hani J. Marcus, Pedro T. Ramirez, Danyal Z. Khan, Hugo Layard Horsfall in Nature Medicine (2024)

  4. Article

    The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring

    The next generation of surgical robotics is poised to disrupt healthcare systems worldwide, requiring new frameworks for evaluation. However, evaluation during a surgical robot’s development is challenging due...

    Hani J. Marcus, Pedro T. Ramirez, Danyal Z. Khan, Hugo Layard Horsfall in Nature Medicine (2024)

  5. Article

    Open Access

    Reported baseline variables in transsphenoidal surgery for pituitary adenoma over a 30 year period: a systematic review

    Heterogeneous reporting in baseline variables in patients undergoing transsphenoidal resection of pituitary adenoma precludes meaningful meta-analysis. We therefore examined trends in reported baseline variabl...

    Hugo Layard Horsfall, Ryan T. S. Loh, Ashwin Venkatesh, Danyal Z. Khan in Pituitary (2023)

  6. Article

    Open Access

    Lived experience-centred word clouds may improve research uncertainty gathering in priority setting partnerships

    AO Spine RECODE-DCM was a multi-stakeholder priority setting partnership (PSP) to define the top ten research priorities for degenerative cervical myelopathy (DCM). Priorities were generated and iteratively re...

    Oliver D. Mowforth, Lance Burn, Danyal Z. Khan in BMC Medical Research Methodology (2023)

  7. No Access

    Chapter and Conference Paper

    A Multi-task Network for Anatomy Identification in Endoscopic Pituitary Surgery

    Pituitary tumours are in an anatomically dense region of the body, and often distort or encase the surrounding critical structures. This, in combination with anatomical variations and limitations imposed by en...

    Adrito Das, Danyal Z. Khan in Medical Image Computing and Computer Assis… (2023)

  8. Article

    Open Access

    Reducing prediction volatility in the surgical workflow recognition of endoscopic pituitary surgery

    Workflow recognition can aid surgeons before an operation when used as a training tool, during an operation by increasing operating room efficiency, and after an operation in the completion of operation notes....

    Adrito Das, Sophia Bano in International Journal of Computer Assisted… (2022)

  9. Article

    Open Access

    Robotic Handle Prototypes for Endoscopic Endonasal Skull Base Surgery: Pre-clinical Randomised Controlled Trial of Performance and Ergonomics

    Endoscopic endonasal skull base surgery is a promising alternative to transcranial approaches. However, standard instruments lack articulation, and thus, could benefit from robotic technologies. The aim of thi...

    Emmanouil Dimitrakakis, Holly Aylmore, Lukas Lindenroth in Annals of Biomedical Engineering (2022)

  10. Article

    Open Access

    Pituitary society expert Delphi consensus: operative workflow in endoscopic transsphenoidal pituitary adenoma resection

    Surgical workflow analysis seeks to systematically break down operations into hierarchal components. It facilitates education, training, and understanding of surgical variations. There are known educational de...

    Hani J. Marcus, Danyal Z. Khan, Anouk Borg, Michael Buchfelder in Pituitary (2021)

  11. Article

    Open Access

    Skull base repair following endonasal pituitary and skull base tumour resection: a systematic review

    Postoperative cerebrospinal fluid rhinorrhoea (CSFR) remains a frequent complication of endonasal approaches to pituitary and skull base tumours. Watertight skull base reconstruction is important in preventing...

    Danyal Z. Khan, Ahmad M. S. Ali, Chan Hee Koh, Neil L. Dorward, Joan Grieve in Pituitary (2021)

  12. Article

    Open Access

    The development of lived experience-centered word clouds to support research uncertainty gathering in degenerative cervical myelopathy: results from an engagement process and protocol for their evaluation, via a nested randomized controlled trial

    AO Spine REsearch objectives and Common Data Elements for Degenerative Cervical Myelopathy [RECODE-DCM] is a multi-stakeholder consensus process aiming to promote research efficiency in DCM. It aims to establi...

    Benjamin M. Davies, Oliver D. Mowforth, Danyal Z. Khan, **aoyu Yang in Trials (2021)

  13. Article

    Open Access

    Trends in cerebrospinal fluid leak rates following the extended endoscopic endonasal approach for anterior skull base meningioma: a meta-analysis over the last 20 years

    The extended endoscopic approach provides unimpaired visualization and direct access to ventral skull base pathology, but is associated with cerebrospinal fluid (CSF) leak in up to 25% of patients. To evaluate...

    Amir H. Zamanipoor Najafabadi, Danyal Z. Khan, Ivo S Muskens in Acta Neurochirurgica (2021)

  14. Article

    Open Access

    The endoscope-assisted supraorbital “keyhole” approach for anterior skull base meningiomas: an updated meta-analysis

    The gold-standard treatment for symptomatic anterior skull base meningiomas is surgical resection. The endoscope-assisted supraorbital “keyhole” approach (eSKA) is a promising technique for surgical resection ...

    Danyal Z. Khan, Ivo S. Muskens, Rania A. Mekary in Acta Neurochirurgica (2021)

  15. Article

    Open Access

    Cellular infiltration in traumatic brain injury

    Traumatic brain injury leads to cellular damage which in turn results in the rapid release of damage-associated molecular patterns (DAMPs) that prompt resident cells to release cytokines and chemokines. These ...

    Aftab Alam, Eric P. Thelin, Tamara Tajsic, Danyal Z. Khan in Journal of Neuroinflammation (2020)