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Article
Investigating the Potential Therapeutic Mechanisms of Puerarin in Neurological Diseases
Plants and their derived phytochemicals have a long history of treating a wide range of illnesses for several decades. They are believed to be the origin of a diverse array of medicinal compounds. One of the c...
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Article
Open AccessAntibacterial efficacy of synthesized silver nanoparticles of Microbacterium proteolyticum LA2(R) and Streptomyces rochei LA2(O) against biofilm forming meningitis causing microbes
Actinobacteria obtained from the least explored Indian regions were studied for their ability to suppress meningitis-causing bacteria in nanoparticle form. Drug-resistant bacteria and long-term treatment with ...
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Article
Open AccessIn silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study, bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α, which is a protein encoded by CSNK2A1
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Article
Open AccessCRISPR/SpCas9-mediated KO of epigenetically active MORC proteins increases barley resistance to Bipolaris spot blotch and Fusarium root rot
Microrchidia (MORC) proteins are fundamental regulators of genome stabilization, chromatin remodeling and gene expression in both mammals and plants. In Arabidopsis, their activity is linked to the RNA-directe...
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Article
Open AccessMolecular Insights into Therapeutic Potentials of Hybrid Compounds Targeting Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the most complex progressive neurological disorders involving degeneration of neuronal connections in brain cells leading to cell death. AD is predominantly detected among el...
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Article
Swelling of multi-responsive spherical polyelectrolyte brushes across a wide range of grafting densities
Multi-stimulus responsive weak polyelectrolyte brushes were grafted by surface-initiated atom transfer radical polymerization from spherical silica nanoparticles across a wide range of grafting densities appro...
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Chapter
Quality Aspects of Cotton Lint
Cotton is the key natural fibre used in the textile industry, the quality of which is extremely critical for successful processing. Many factors influence its fibre quality. The fibre quality of the open boll ...
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Chapter
Secondary Metabolites from Rosemary (Rosmarinus officinalis L.): Structure, Biochemistry and Therapeutic Implications Against Neurodegenerative Diseases
Rosemary (Rosmarinus officinalis L.), the representative of Lamiaceae family is known for its various medicinal uses that are accompanied by their hallmark secondary metabolites, i.e., carnosol, carnosic acid and...
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Article
Open AccessExtenuating the role of Ficus virens Ait and its novel bioactive compound on antioxidant defense system and oxidative damage in cigarette smoke exposed rats
Production of free radicals is associated with cigarette smoke (CS) which in turn generates oxidative stress, could be responsible for alterations in the activities of enzymatic and non-enzymatic antioxidants ...
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Article
Open AccessPredicting the behavior of microfluidic circuits made from discrete elements
Microfluidic devices can be used to execute a variety of continuous flow analytical and synthetic chemistry protocols with a great degree of precision. The growing availability of additive manufacturing has en...
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Article
Open AccessBioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait
The current perspective for the search of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor has been shifted towards a natural agent also having antioxidant property. Thus, this study was in...
