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Open AccessWhole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study
Klebsiella spp. are opportunistic pathogens which can cause severe infections, are often multi-drug resistant and are a common cause of hospital-acquired infections. Multiple new Klebsiella species have recently ...
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Article
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
The ability of gut bacterial pathogens to escape immunity by antigenic variation—particularly via changes to surface-exposed antigens—is a major barrier to immune clearance1. However, not all variants are equally...
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Article
Publisher Correction: Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm
The western corn rootworm (WCR) decimates maize crops worldwide. One potential way to control this pest is treatment with entomopathogenic nematodes (EPNs) that harbor bacterial symbionts that are pathogenic t...
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Article
Open AccessProsthetic valve endocarditis caused by Pseudomonas aeruginosa with variable antibacterial resistance profiles: a diagnostic challenge
Infective endocarditis (IE) caused by gram-negative bacilli is rare. However, the incidence of this severe infection is rising because of the increasing number of persons at risk, such as patients with immunos...
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Article
Open AccessA point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence
The polysaccharide capsule is a major virulence factor of the important human pathogen Streptococcus pneumoniae. However, S. pneumoniae strains lacking capsule do occur.
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Article
Open AccessProteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry
Trypanosoma brucei is the causative agent of human African slee** sickness and Nagana in cattle. In addition to being an important pathogen T. brucei has developed into a model system in cell biology.
