6 Result(s)
within
Daniel Reimer
Oncology
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Article
Open AccessPARP inhibitors in the treatment of ovarian cancer
The recent exciting findings on the use of poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitor (PARPi) maintenance therapy in the first-line and later lines of treatment in ovarian cancer are illustr...
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Article
Open AccessEvaluation of Vav3.1 as prognostic marker in endometrial cancer
Vav3 is a guanine nucleotide exchange factor that regulates the activity of Rho/Rac family GTPases. In a study on ovarian cancer, we recently demonstrated pronounced prognostic and predictive value of Vav3.1, ...
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Article
Open AccessEvaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promoter methylation and global DNA hypomethylation in type I and type II ovarian cancers
In this retrospective study we evaluated the respective correlations and clinical relevance of FOLR1 mRNA expression, FOLR1 promoter specific methylation and global DNA hypomethylation in type I and type II ov...
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Article
Open AccessExpression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer
An increasing body of evidence shows that miR-34 family has tumor suppressive properties mediating apoptosis, cell cycle arrest and senescence. In ovarian cancer, miR34 family members were found to be under ex...
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Article
Urinary neopterin does not reflect the local antitumor immune milieu in ovarian cancer
The main objective of the present investigation was to study the urinary neopterin excretion in the context of the activation of the adaptive cellular immune system at the tumor site. For this purpose, we comp...
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Article
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer
This study analyzes the relationship between coxsackie-adenovirus receptor (CAR) expression (transmembrane and soluble isoforms) and hormone sensitivity in 95 breast cancers. Furthermore, prognostic significan...
