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Open AccessThe zygoma anatomy-guided approach (ZAGA) for rehabilitation of the atrophic maxilla
A protocol to perform a prosthetically driven minimally invasive zygomatic osteotomy, named zygoma anatomy-guided approach (ZAGA) is introduced. The ZAGA method aims at promoting a patient-specific therapy by ...
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Fire in Forest Ecosystems: Processes and Management Strategies
There have been fires on this planet for 420 million years – especially since (a) the oxygen content of the atmosphere has exceeded 13% and (b) land plants have been available for combustion, with lightning st...
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Article
Open AccessDefinition of acute kidney injury impacts prevalence and prognosis in ACS patients undergoing coronary angiography
Development of acute kidney injury (AKI) in invasively managed patients with acute coronary syndrome (ACS) is associated with a markedly increased mortality risk. Different definitions of AKI are in use, leadi...
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Article
Open AccessSouthern Canada’s crisis ecoregions: identifying the most significant and threatened places for biodiversity conservation
Identifying and protecting key areas for biodiversity is a cornerstone of effective nature conservation. This conservation assessment analyzes 77 ecoregions across the southern, settled part of Canada to ident...
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Free Space Optics System Reliability in the Presence of Weather-Induced Disruptions
Free space optics (FSO) is a wireless optical communication technology enabling extremely high data transmission rates, which can be used for a wide range of emerging applications. Nevertheless, FSO system rel...
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Article
Model distances for vine copulas in high dimensions
Vine copulas are a flexible class of dependence models consisting of bivariate building blocks and have proven to be particularly useful in high dimensions. Classical model distance measures require multivaria...
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Otto-Turbolader mit variabler Turbinentechnologie
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Gasoline Turbocharger with Variable Turbine Technology
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A matter of time: self-regulated tree regeneration in a natural Norway spruce (Picea abies) forest at Mt. Brocken, Germany
European natural mountain Norway spruce (Picea abies) forests are currently subject to extensive disturbances. An improved understanding of the self-regulated regenerative capacity of this forest type is therefor...
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Article
Open AccessABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy
Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of human bre...
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Comparison of integrative nature conservation in forest policy in Europe: a qualitative pilot study of institutional determinants
In this pilot study, we examine the relationship between the organisation of property rights and the economic importance of forestry on the one hand and the degree to which integrative nature conservation is f...
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Open AccessBiguanide therapy for diabetes and cancer & a novel methyltransferase that regulates energy expenditure and adiposity and is elevated in many cancers
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Article
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
Nicotinamide N-methyltransferase (NNMT) expression is increased in white adipose tissue and liver of obese and diabetic mice, Nnmt knockdown protects against diet-induced obesity by altering the availability of a...
