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  1. Article

    Open Access

    Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway

    Glucagon-like peptide-1 (GLP-1) is a hormone predominately synthesized and secreted by intestinal L-cells. GLP-1 modulates multiple cellular functions and its receptor agonists are now used clinically for diab...

    Yong-Fu **ao, Alena Nikolskaya, Deborah A Jaye, Daniel C Sigg in Cardiovascular Diabetology (2011)

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  2. No Access

    Book

    Cardiac Electrophysiology Methods and Models

    Daniel C. Sigg, Paul A. Iaizzo… (2010)

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    Chapter

    Basic Cardiac Electrophysiology: Excitable Membranes

    Cardiomyocytes are excitable cells that have the ability to contract after excitation; therefore, each heartbeat is an event of electrical–mechanical coupling. Cardiac electrical activity at different levels c...

    Deborah A. Jaye, Yong-Fu **ao… in Cardiac Electrophysiology Methods and Mode… (2010)

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    Chapter

    Reversible and Irreversible Damage of the Myocardium: New Ischemic Syndromes, Ischemia/Reperfusion Injury, and Cardioprotection

    Ischemia and reperfusion injuries can lead to major compromises in cardiac function. While the intent of many of the past cardioprotective therapies was to protect the myocardium from ischemic necrosis, it may...

    James A. Coles, Daniel C. Sigg… in Handbook of Cardiac Anatomy, Physiology, a… (2009)

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    Chapter

    Cardiac and Vascular Receptors and Signal Transduction

    Cellular physiological functions are regulated via signaling mechanisms in essentially any cell type of any organ. While myocardial cells are unique in that they are interconnected to each other via gap juncti...

    Daniel C. Sigg, Ayala Hezi-Yamit in Handbook of Cardiac Anatomy, Physiology, and Devices (2009)