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Article
Open AccessStructural basis for clearing of ribosome collisions by the RQT complex
Translation of aberrant messenger RNAs can cause stalling of ribosomes resulting in ribosomal collisions. Collided ribosomes are specifically recognized to initiate stress responses and quality control pathway...
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Article
Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation
CD95L is a transmembrane ligand (m-CD95L) that is cleaved by metalloproteases to release a soluble ligand (s-CD95L). Unlike m-CD95L, interaction between s-CD95L and CD95 fails to recruit caspase-8 and FADD to ...
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Chapter and Conference Paper
Gamification for Measuring Cyber Security Situational Awareness
Cyber defense competitions arising from U.S. service academy exercises, offer a platform for collecting data that can inform research that ranges from characterizing the ideal cyber warrior to describing behav...