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  1. Article

    Open Access

    Structural basis for clearing of ribosome collisions by the RQT complex

    Translation of aberrant messenger RNAs can cause stalling of ribosomes resulting in ribosomal collisions. Collided ribosomes are specifically recognized to initiate stress responses and quality control pathway...

    Katharina Best, Ken Ikeuchi, Lukas Kater, Daniel Best in Nature Communications (2023)

  2. No Access

    Article

    Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation

    CD95L is a transmembrane ligand (m-CD95L) that is cleaved by metalloproteases to release a soluble ligand (s-CD95L). Unlike m-CD95L, interaction between s-CD95L and CD95 fails to recruit caspase-8 and FADD to ...

    Amanda Poissonnier, Jean-Philippe Guégan, Ha Thanh Nguyen in Nature Chemical Biology (2018)

  3. Chapter and Conference Paper

    Gamification for Measuring Cyber Security Situational Awareness

    Cyber defense competitions arising from U.S. service academy exercises, offer a platform for collecting data that can inform research that ranges from characterizing the ideal cyber warrior to describing behav...

    Glenn Fink, Daniel Best, David Manz in Foundations of Augmented Cognition (2013)