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Open AccessFunctional analysis of the mating type genes in Verticillium dahliae
Populations of the plant pathogenic fungus Verticillium dahliae display a complex and rich genetic diversity, yet the existence of sexual reproduction in the fungus remains contested. As pivotal genes, MAT genes ...
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Article
The level of CmFRQ is associated with the degeneration and rejuvenation of Cordyceps militaris fruiting body
Cordyceps militaris is a large fungus whose fruiting body is prone to degeneration. In the study of C. militaris FREQUENCY (CmFRQ), the negative regulator of C. militaris circadian clock, it was found that after ...
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Article
Open AccessRGS5 maintaining vascular homeostasis is altered by the tumor microenvironment
Regulator of G protein signaling 5 (RGS5), as a negative regulator of G protein-coupled receptor (GPCR) signaling, is highly expressed in arterial VSMCs and pericytes, which is involved in VSMC phenotypic hete...
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Article
Open AccessTwo zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae
Melanin plays important roles in morphological development, survival, host–pathogen interactions and in the virulence of phytopathogenic fungi. In Verticillum dahliae, increases in melanin are recognized as marke...
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Article
Open AccessGenome-wide identification and analysis of a cotton secretome reveals its role in resistance against Verticillium dahliae
The extracellular space between the cell wall and plasma membrane is a battlefield in plant-pathogen interactions. Within this space, the pathogen employs its secretome to attack the host in a variety of ways,...
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Article
Differential ubiquitome analysis of Cordyceps militaris lysine-ubiquitinated proteins affected by blue light
Blue light is a very important environmental factor, which plays an important role in regulating the growth and development of organisms. Studies have shown that blue light plays a decisive role in the develop...
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Open AccessA polyketide synthase from Verticillium dahliae modulates melanin biosynthesis and hyphal growth to promote virulence
During the disease cycle, plant pathogenic fungi exhibit a morphological transition between hyphal growth (the phase of active infection) and the production of long-term survival structures that remain dormant...
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Article
Open AccessVerticillium dahliae CFEM proteins manipulate host immunity and differentially contribute to virulence
Verticillium dahliae is a fungal pathogen that causes a vascular wilt on many economically important crops. Common fungal extracellular membrane (CFEM) domain proteins including secreted types have been implicate...
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Article
Open AccessIonotropic receptors in the turnip moth Agrotis segetum respond to repellent medium-chain fatty acids
In insects, airborne chemical signals are mainly detected by two receptor families, odorant receptors (ORs) and ionotropic receptors (IRs). Functions of ORs have been intensively investigated in Diptera and Le...
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Article
Open AccessCorrection: Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
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Open AccessSmooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We found a potent...
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Article
Open AccessExosomal microRNA-15a from mesenchymal stem cells impedes hepatocellular carcinoma progression via downregulation of SALL4
Hepatocellular carcinoma (HCC) is a heterogeneous tumor with an increased incidence worldwide accompanied by high mortality and dismal prognosis. Emerging evidence indicates that mesenchymal stem cells (MSCs)-...
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Open AccessDynamics of Verticillium dahliae race 1 population under managed agricultural ecosystems
Plant pathogens and their hosts undergo adaptive changes in managed agricultural ecosystems, by overcoming host resistance, but the underlying genetic adaptations are difficult to determine in natural settings. V...
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Article
Open AccessPutative ligand binding sites of two functionally characterized bark beetle odorant receptors
Bark beetles are major pests of conifer forests, and their behavior is primarily mediated via olfaction. Targeting the odorant receptors (ORs) may thus provide avenues towards improved pest control. Such an ap...