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  1. Article

    Open Access

    Effects of working memory load and CS-US intervals on delay eyeblink conditioning

    Eyeblink conditioning is used in many species to study motor learning and make inferences about cerebellar function. However, the discrepancies in performance between humans and other species combined with evi...

    Leila Etemadi, Dan-Anders Jirenhed, Anders Rasmussen in npj Science of Learning (2023)

  2. No Access

    Reference Work Entry In depth

    Purkinje Neurons During Eye Blink Conditioning and New Mechanisms of Cerebellar Learning and Timing

    During eyeblink conditioning, Purkinje cells that control blinking develop an inhibitory response to the conditional stimulus. This conditional response (CR) in the Purkinje cell shows a number of striking sim...

    Germund Hesslow, Dan-Anders Jirenhed in Handbook of the Cerebellum and Cerebellar … (2022)

  3. No Access

    Chapter and Conference Paper

    Timing in Purkinje Cells and a Novel Learning Mechanism

    During eyeblink conditioning, Purkinje cells that control the eyelid learn to respond with a pause in simple spike firing to the conditional stimulus. This conditional pause response (CR) in the Purkinje cell ...

    Germund Hesslow, Dan-Anders Jirenhed, Fredrik Johansson in Cerebellum as a CNS Hub (2021)

  4. No Access

    Living Reference Work Entry In depth

    Purkinje Neurons During Eye Blink Conditioning and New Mechanisms of Cerebellar Learning and Timing

    During eyeblink conditioning, Purkinje cells that control blinking develop an inhibitory response to the conditional stimulus. This conditional response (CR) in the Purkinje cell shows a number of striking sim...

    Germund Hesslow, Dan-Anders Jirenhed in Handbook of the Cerebellum and Cerebellar …

  5. Article

    Open Access

    Absence of Parallel Fibre to Purkinje Cell LTD During Eyeblink Conditioning

    Long-term depression (LTD) of parallel fibre/Purkinje cell synapses has been the favoured explanation for cerebellar motor learning such as classical eyeblink conditioning. Previous evidence against this inter...

    Fredrik Johansson, Dan-Anders Jirenhed, Anders Rasmussen in Scientific Reports (2018)

  6. Article

    Open Access

    Learning and Timing of Voluntary Blink Responses Match Eyeblink Conditioning

    Can humans produce well-timed blink responses to a neutral stimulus voluntarily, without receiving any blink-eliciting, unconditional, stimulus? And if they can, to what degree does classical eyeblink conditio...

    Anders Rasmussen, Dan-Anders Jirenhed in Scientific Reports (2017)

  7. Article

    Open Access

    Are Purkinje Cell Pauses Drivers of Classically Conditioned Blink Responses?

    Several lines of evidence show that classical or Pavlovian conditioning of blink responses depends on the cerebellum. Recordings from cerebellar Purkinje cells that control the eyelid and the conditioned blink...

    Dan-Anders Jirenhed, Germund Hesslow in The Cerebellum (2016)

  8. No Access

    Article

    Learning Stimulus Intervals—Adaptive Timing of Conditioned Purkinje Cell Responses

    Classical conditioning of motor responses, such as the eyeblink response, is an experimental model of associative learning and of adaptive timing of movements. A conditioned blink will have its maximum amplitu...

    Dan-Anders Jirenhed, Germund Hesslow in The Cerebellum (2011)

  9. No Access

    Article

    Simple and Complex Spike Firing Patterns in Purkinje Cells During Classical Conditioning

    Classical blink conditioning is known to depend critically on the cerebellum and the relevant circuitry is gradually being unravelled. Several lines of evidence support the theory that the conditioned stimulus...

    Anders Rasmussen, Dan-Anders Jirenhed, Germund Hesslow in The Cerebellum (2008)