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Article
Open AccessExploring new avenues of health protection: plant-derived nanovesicles reshape microbial communities
Symbiotic microbial communities are crucial for human health, and dysbiosis is associated with various diseases. Plant-derived nanovesicles (PDNVs) have a lipid bilayer structure and contain lipids, metabolite...
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Article
Open AccessWNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathway
5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. There...
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Article
Open AccessInvestigating diagnostic potential of long non-coding RNAs in head and neck squamous cell carcinoma using TCGA database and clinical specimens
Head and neck squamous cell carcinoma (HNSCC) is a prevalent and prognostically challenging cancer worldwide. The role of long non-coding RNAs (lncRNAs) in cancer regulation is progressively being understood. ...
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Article
Open AccessIL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1
Matrix metalloproteinase-1 (MMP1) has an aberrant expression relevant to various behaviors of cancers. As dominant components of the tumor stroma, fibroblasts constitute an important source of Matrix metallopr...
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Article
Open AccessWNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling
Wnt signaling are critical pathway involved in organ development, tumorigenesis, and cancer progression. WNT7A, a member of the Wnt family, remains poorly understood in terms of its role and the underlying mol...
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Article
Open AccessPlant-derived nanovesicles: harnessing nature's power for tissue protection and repair
Tissue damage and aging lead to dysfunction, disfigurement, and trauma, posing significant global challenges. Creating a regenerative microenvironment to resist external stimuli and induce stem cell differenti...
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Article
Open AccessAntitumor effect of toosendanin on oral squamous cell carcinoma via suppression of p-STAT3
Toosendanin (TSN) exhibits potent antitumor activity against various tumor cell lines. However, its efficacy against oral squamous cell carcinoma (OSCC) remains unknown. Here, we investigated the effects of TS...
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Article
Parameter design of active dam**-based shunt hybrid active power filters
This paper presents the parameter design of a new topology of hybrid active power filter (HAPF), which makes the system capacity smaller. Based on the main topological circuit, the passive LC single-tuned circ...
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Article
Open AccessElevated matrix metalloproteinase 7 expression promotes the proliferation, motility and metastasis of tongue squamous cell carcinoma
Matrix metalloproteinase 7 (MMP7), as the smallest member of the matrix metalloproteinase family, has been verified to be implicated in cancer progression, especially metastasis. However, its expression patter...
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Article
Nanopore-based detection of circulating microRNAs in lung cancer patients
MicroRNAs are short RNA molecules that regulate gene expression, and have been investigated as potential biomarkers because their expression levels are correlated with various diseases. However, detecting micr...
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Article
Buckling of a ferromagnetic thin plate in a transverse static magnetic field
An energy theory is proposed on the buckling of a ferromagnetic thin plate in a transverse static magnetic field. The analytic solution of critical field for plates is obtained by using variational method. It ...
